Morquio disease in a patient diagnosed as having perthes disease for 38 years

Spondyloepiphyseal Dysplasias and Bilateral Legg-Calvé-Perthes Disease: Diagnostic Considerations for Mucopolysaccharidoses

“…Fang-Kircher et al describe a 51-year-old man diagnosed with MPS IVA who had previously been thought to have Perthes disease identified at 13 years of age (Fang-Kircher et al 1995). Prat et al describe a 38-year-old woman who had marked short stature, prognathism, short trunk and neck, kyphoscoliosis, genu valgum, and pes planus.…”

Femoral head dysplasia in Morquio disease type A: Bilateral varus osteotomy of the femur

“…Although mild forms of Morquio disease tend to be misdiagnosed as disorders of the hip, such as Perthes' disease (Fang-Kircher et al 1995), in cases of bilateral coxarthropathy, bone dysplasia should be suspected first, and radiographs of other joints, spine, hands, and feet, along with physical examination and family history, should be studied. We believe ophthalmoscopic examination is important.…”

Bilateral hip replacement in three patients with lysosomal storage disease: Mucopolysaccharidosis type IV and Mucolipidosis type III

“…These disorders present a wide spectrum of disease and although hip pathology is well recognised, in the milder forms, particularly Morquio disease, it is occasionally misdiagnosed as Perthes' disease. 20 It is important to remember that in cases of early bilateral arthritis of the hips, bone dysplasia should be suspected and radiographs of the other joints, including the spine, hands and feet should be undertaken along with a physical examination and obtaining a family history. 21 Milder forms of these conditions with hip disorders have been successfully treated with bilateral varus osteotomies although long-term follow-up has not been conducted.…”