Morphometric study of ventricular myocardial cells in the bat (pipistrellus pipistrelle) hamster (mesocricetus auratus) and the wistar rat

Ayettey, A.S.; Yates, R.D.

doi:10.1016/s0022-2828(87)80780-0

Cited by 2 publications

(2 citation statements)

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“…Although overall these organelles form 41% of the cytoplasmic volume [9], their cristae are widely spaced when compared with those of the rat and mouse. This represents a major difference in mitochondria of the fruit-eating bat and those of the insect eating bat P. pipistrellus, in which we have reported a very high density of mitochondrial cristae [2], Unlike most cardiac cells, lipid bodies are frequently seen in the matrix of mitochondria. This feature of the rela tionship between mitochondria and lipid bodies is neither artefactual nor could it be attributed to ischemia [25] since cardiac cells of the rat and mouse prepared under similar conditions did not show evidence of lipid infiltration into mitochondria.…”

Section: Discussionmentioning

confidence: 62%

Ultrastructural Characteristics of Atrial, Ventricular and Subendocardial (Purkinje) Cells of the Fruit-Eating Bat <i>Eidolon helvum</i>

Ayettey¹,

Tagoe²,

Yates³

1993

Cells Tissues Organs

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The ultrastructure of the myocardium of the large (285 gm) fruit-eating bat (Eidolon helvum) provides further evidence that, among mammalian species, different types of cardiac myocytes are morphologically heterogeneous. Atrial cells of this species, like those of smaller bats previously studied, have few of the natriuretic hormone-containing granules. These granules are also small, with a mean diameter of 176 ± 3.9 nm in comparison with those of the rat (230 ± 5.8 nm) and mouse (211 ± 4.7 nm). In all types of myocytes of the bat investigated, mito-chondrial matrix granules are more prominent than in those of the rat and mouse. Also distinctive are the Purkinje cells which, aside from their large size (30 µm) and lack of T-tubules, have atrial granule-like inclusions. These cells are well endowed with mitochondria (28% of cytoplasmic volume) and with lipid bodies but have few glycogen granules. Their myofibrillae (33%) are well aligned. The ventricular cells (average diameter 14 µm) have nearly equal volumes of mitochondria (41%) and myofibrils (47%). Mitochondrial cristae, however, are not compactly organized. Lipid material is found in the matrix of the mitochondria. Extensive evaginations of endothelial cells of the bat endocardium appear continuous with endothelial vacuoles. In these endothelial cells, there are also many dense granules of varying shapes and sizes.

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Section: Discussionmentioning

confidence: 62%

Ultrastructural Characteristics of Atrial, Ventricular and Subendocardial (Purkinje) Cells of the Fruit-Eating Bat <i>Eidolon helvum</i>

Ayettey¹,

Tagoe²,

Yates³

1993

Cells Tissues Organs

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“…In contrast to cattle, sheep and pig, where the conductive system is built up from large highly differentiated cells, this system is less differentiated in man (Canale eta]., 1986). According to the differences in morphology, functional differences have to be expected (Ayettey et aL, 1991). Henry & Lowry (1983), however, also found that the LDH activity in microdissected tissue of the conducting system is lower, at a ratio of 0.61:1 compared with the myocardium.…”

Section: Discussionmentioning

confidence: 98%

Microquantitative determination of lactate dehydrogenase isoenzymes in the myocardium and the conducting system

et al. 1994

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A newly developed technique was used for the electrophoretic separation of lactate dehydrogenase (LDH) isoenzymes from lyophilized tissue samples in the nanogram range. In this study portions of 10-200 ng from the myocardium and the conducting system of cattle, sheep, pig and man were microdissected and analysed. In the heart tissues of cattle, sheep and pig, the isoforms LDH1, LDH2 and LDH3 were detected in species-specific varying amounts. In all these animals, the conducting system is marked by high LDH1 activity, which is present at a ratio of about 2:1 compared with the myocardium. The values in man, however, differ from these values, but this might be due to post-mortem changes. The findings are discussed with respect to possible aerobic-anaerobic functions.

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Morphometric study of ventricular myocardial cells in the bat (pipistrellus pipistrelle) hamster (mesocricetus auratus) and the wistar rat

Cited by 2 publications

References 0 publications

Ultrastructural Characteristics of Atrial, Ventricular and Subendocardial (Purkinje) Cells of the Fruit-Eating Bat <i>Eidolon helvum</i>

Ultrastructural Characteristics of Atrial, Ventricular and Subendocardial (Purkinje) Cells of the Fruit-Eating Bat <i>Eidolon helvum</i>

Microquantitative determination of lactate dehydrogenase isoenzymes in the myocardium and the conducting system

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