Morphology of colorectal carcinoma among Nigerians: A 30-year review

Abstract

Colorectal carcinoma is no longer a rare disease in Nigeria. The surge in the incidence reported in the last 5 years in this center calls for a pragmatic action in its control, with emphasize on colonoscopic screening for those with family history, and possibly making digital rectal examination a mandatory aspect of clinical examination, because most colorectal carcinomas are within the reach of examining finger.

A Comparison of Colorectal Cancer in West African and North American Patients: Is the Cancer Biology Different?

“…Similar to other authors, we found a higher male-tofemale ratio in our West African population. [7][8]10 This male preponderance may be explained by higher suspected rates of male tobacco use and abdominal obesity 5,8 or may reflect a selection bias that results from well-documented gender inequity in access to healthcare. 12 The possibility of different tumor biology is clearest when considering the metastatic pattern observed in the two centers.…”

“…[6][7][8] In Nigeria, Ibrahim et al found that 40% of all CRC cases observed in a 30-year period occurred in the final five years of the study (2004)(2005)(2006)(2007)(2008). Meanwhile the surgical biopsy registry at Lagos University Teaching Hospital has identified CRC as the third most commonly diagnosed malignancy.…”

“…[6][7][8]10 Further, improvements in access to care may also be leading to a higher rate of CRC detection. However, as CRC rates increase in LMIC, outcomes remain poor.…”

“…[3][4][5] Colorectal cancer (CRC) it the third most common cancer in men and the second most common cancer in women worldwide 4 and rising rates have been observed in LMIC. [5][6][7][8] There is a need to examine the etiology, presentation, biology and outcomes of CRC in LMIC and how it may differ from CRC in better-studied parts of the world.…”

Boosting Cancer Survival in Nigeria: Self-management Strategies

“…Liver cancer has risk factors ranging from infection with Hepatitis B or C viruses to alcohol use and food Colorectal cancer is also no longer a rare disease in Nigeria as evidenced in a review which showed that out of 241 cases in the last 30 years, 93 cases were seen in the last 5 years (Ibrahim et al, 2011).…”