Morphology of a prolapsed posterior mitral valve leaflet

Trent, Jennifer; Adelman, Allan G.; Wigle, E. Douglas; Silver, Malcolm D.

doi:10.1016/0002-8703(70)90260-7

Cited by 70 publications

(7 citation statements)

References 13 publications

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“…These findings led some authors to consider the hypothesis of a segmental cardiomyopathy (Gulotta et al, 1974;Koch er al., 1977;Mason era/. , 1978;Trent et al, 1970). Abnormal segmental wall motion has also been shown to occur in pure mitral stenosis-a finding which could also involve subvalvular fibrosis (Cunyet al, 1972;Grant, 1953).…”

Section: Discussionmentioning

confidence: 99%

Untitled

1986

Clinical Cardiology

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Summary:This work attempted to study the segmental wall motion on left ventriculograms, in terms of segmental shortening, velocity of segmental shortening, and temporal sequences of various events in systole as well as in diastole. The ability of such a method to characterize pat-(ems of normal regional wall motion and to detect mild abnormalities such as isolated asynchronisms, was tested on two groups of patients. Group I included 25 patients presenting evidence of a normal left ventricle (LV) after left heart catheterization. Group I1 consisted of 21 patients suffering from an isolated pure idiopathic mitral valve prolapse (MVP), with no mitral insufficiency and with an unaffected global LV function. In all patients left ventnculography was filmed in the right anterior oblique view at a rate of 50 frames/s. For each patient a cycle was chosen, distant from any premature beat, with acceptably contrasted outlines, and a quantitative frame by frame study ofthe motion of 10 segments was performed using a semiautomated method derived from the Stanford method. In the control group (Group I), analysis of the segmental motion by means of this method demonstrates a mild nonuniformity of the normal wall motion. This is prin- vs. Ok0.48 circ/s in Group I, p

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Section: Discussionmentioning

confidence: 99%

Untitled

1986

Clinical Cardiology

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“…The morphology of the mitral valve apparatus and contiguous areas in postmortem and surgically removed specimens has been studied by several authors (Pomerance, 1969;Trent et al, 1970;Perloff and Roberts, 1972;McKay and Yacoub, 1973;Marshall and Shappel, 1974;Silver, 1974). The deformity has been characterised by the presence of voluminous and redundant thickened valve leaflets with a gelatinous consistency.…”

Section: Discussionmentioning

confidence: 99%

Hemiplegia and the billowing mitral leaflet syndrome.

Hirsowitz¹,

Saffer²

1978

Journal of Neurology, Neurosurgery & Psychiatry

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“…Whether or not the non-specific ST and T wave changes are taken as evidence of a disorder in the myocardium, it is possible that they may identify a group of patients who are at high risk from arrhythmias. In support of this suggestion are the 11 reported patients with balloon deformity of the mitral valve who died suddenly or had ventricular fibrillation, and for whom electrocardiographic data are available: 8 had the auscultatoryelectrocardiographic variant of the syndrome and 3 showed QT prolongation (Hancock and Cohn, 1966;Barlow et al, 1968;Trent et al, 1970;Jeresaty, 1973;Marshall and Shappell, 1974;Rakowski et al, 1975). These results and the previous reports of sudden death suggest that it is important to diagnose this condition.…”

Section: Echocardiographymentioning

confidence: 95%

“…In most patients the balloon deformity has little haemodynamic consequence but the condition has been associated with ventricular and supraventricular arrhythmias (Hancock and Cohn, 1966;Kreisman et al, 1971;Gooch et al, 1972;Sloman, Wong, and Walker, 1972;Jeresaty, 1973;Rizzon et al, 1973;DeMaria et al, 1974;Gulotta et al, 1974;Schaal, Fontana, and Wooley, 1974;Winkle et al, 1975), and sudden death has been reported in 9 patients (Hancock and Cohn, 1966;Barlow et al, 1968;Trent et al, 1970;Jeresaty, 1973;Marshall and Schappell, 1974;Rakowski et al, 1975). The incidence of the lesion is not known accurately but in a recent necropsy series the abnormality was detected in 0'33 per cent of the population studied (Rizzon et al, 1973), and clinical reports have suggested incidences from 6 to 10 per cent (Markiewicz et al, 1975;Brown, Kloster, and DeMots, 1975;Procacci et al, 1975).…”

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confidence: 99%

Ventricular arrhythmias in syndrome of balloon deformity of mitral valve. Definition of possible high risk group.

Campbell¹,

Godman²,

Fiddler³

et al. 1976

Heart

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Twenty patients clinically identified as having balloon deformity of the mitral valve were studied to assess the incidence of ventricular arrhythmias. Echocardiography and phonocardiography were used to confirm the nature of the mitral valve lesion. Continuous 24-hour electrocardiograms were obtainedfrom all patients and analysed by a computer and 2 observers. One patient had ventricularfibrillation and 3 patients had ventricular tachycardia. There was a high incidence of other less severe forms of ventricular arrhythmis. Eight patients had inferolateral ST and T wave abnormality on the resting electrocardiogram, and were described as having the auscultatory-electrocardiographic variant of the balloon mntral valve syndrome. The occurrence of serious ventricular arrhythmias (ventricular fibrillation and tachycardia) was s4igficantly more frequent in this group. This raises the possibility that the resting electrocardiogram may identify those patients with balloon deformity of the mitral valve who are at risk from sudden death.

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Morphology of a prolapsed posterior mitral valve leaflet

Cited by 70 publications

References 13 publications

Untitled

Untitled

Hemiplegia and the billowing mitral leaflet syndrome.

Ventricular arrhythmias in syndrome of balloon deformity of mitral valve. Definition of possible high risk group.

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