Morphology and Thermal Characteristics of Polyamide/Monosodium Glutamate Membranes

Abstract

The membranes were prepared with various concentrations of polyamide and monosodium glutamate additive for dialysis application in this work. The membranes were characterized by determining creatinine diffusive permeability and by obtaining scanning electron microscope images and thermal characteristics. The results show that a membrane prepared without additive has a thick skin layer and a nonporous sublayer. The permeation of creatinine solute does not take place due to this dense (thick/nonporous) structure. When an additive is used in membrane synthesis, the thickness of skin layer reduces and voids are present, which results in permeation of this unwanted solute through the membrane.

In vitro cytocompatibility and blood compatibility of polysulfone blend, surface-modified polysulfone and polyacrylonitrile membranes for hemodialysis

“…Carbon nanotube-graed PES composite membranes, 16 chemically modied PSf, 17 vitamin E-TPGS (D-a-tocopheryl polyethylene glycol 1000 succinate) composite membranes, 18 and polyamide and monosodium glutamate blend membranes have also been explored for dialysis applications. 19,20 However, biocompatibility is not the only issue for the selection of membranes by practising clinicians. The development of highperformance membranes has become a pivotal issue in dialysis treatment, since higher and faster clearance of uremic toxins increases the patients' longevity.…”