Morphology and Morphometric Study of Human Placenta in Rural Southern India

Abstract

Aims: To study the morphology and do the morphometric analysis of placenta and to correlate with the foetal parameters, in order to help in the assessment of the state of well being of foetus. To study the histomorphological features of placenta in various conditions complicating the pregnancy.

Placental changes in hypertensive pregnancy: a comparison with normotensive pregnancy

“…21 In other studies too, its prevalence has been reported to range from 80% to 100% in hypertensive women. 11,15 For other major findings such as cytotrophoblastic cellular proliferation which was seen in 71.4% of cases in hypertensive group and 52.4% of normotensive cases in present study, we found supportive evidence from Nag et al, Motwani et al and Porwal et al 14,16,19 For other major findings too, like hyalinized areas we had 61.9% hypertensive cases and 11.9% normotensive cases. Motwani et al in their study reported hyalinized areas in 46.66% of hypertensive cases and 13.3% of normotensive cases, which is much lower than that reported in present study.…”

“…In different studies, placental weight in hypertensive pregnancies has been reported to vary from 345.96 g to 524.24 g whereas that in normotensive pregnancies ranged from 435.92 g to 557.8 g. 12,13 The difference in placental weight of two groups in present study was 77.77 g. Extent of this difference has ranged widely in different studies. Qureshi et al found this difference to be 33 g only while Motwani et al found it as 67 g, similar to our study, Kulandaivelu et al in their study reported it to be 73 g, however, on a higher note Nag et al found this difference to be as high as 94 g and Salmani et al even surpassed this and reported this difference as 124 g. [13][14][15][16][17] The profile of differences in placental weight between hypertensive group and normotensive groups in different studies might be due to difference in different types of HDPs included in the assessment. Studies reporting a higher difference generally have a higher component of severe HDPs like severe preeclampsia and eclampsia as compared to gestational hypertension.…”

“…0.5cm). 13,15,18,20 In present study, we found them as 1.91 and 2.1 cm with a difference of 0.2 cm only. The reason for variance in placental thickness measurements and difference between the two groups in different studies could be owing to difference in method of measurement in different studies.…”

“…However, Kulandaivelu et al found this difference to be only 1.06 cm, Qureshi et al found this difference to be 1.6 cm, while Singh and Gugapriya found this difference to be somewhat close to that reported in present study at 2.49 cm. 13,15,18 On the other hand, Ranga SS et al reported it as 5 cm. Porwal et al in their study reported this difference in terms of proportion of women with placental diameter <20 cm to be 90% in hypertensive group as compared to 63.33% in normotensive group.…”

Variability of the Human Placental Shapes in Normal and Pre-Eclamptic Pregnancies and Its Effects on Placental and Foetal Outcomes

“…[9,10,11] In the present study, the shape of the placenta was found to be discoidal in 62.5% cases and oval in 30% cases of the control group, whereas in pre-eclamptic group oval shaped placentae were found in 52.5% cases and discoidal shaped placentae were found in 30% cases [ Table 1]. These findings suggested that discoidal and oval-shaped placentae were common in both groups.…”