MORPHOLOGICAL STUDY ON THE PRODUCTION AND SECRETION MECHANISM OF HUMAN CHORIONIC GONADOTROPIN (hCG)

AN IMMUNOHISTOLOGICAL STUDY OF DISTRIBUTION OF BETA-SUBUNIT OF HUMAN CHORIONIC GONADOTROPIN (hCG-β) IN TROPHOBLAST-LIKE CELLS IN THE LUNG TUMOR

“…Granular distribution was not seen in either tissue of the tumor, which is a characteristic pattern to hCG-/3 in normal placental trophoblast (14). These findings suggest that they may be related to either heterogeneity of hCG-/3 (23) or the difference of cell constituents in connection with synthesis and secretion of hCG-,8 between tumor and normal placental trophoblast.…”

Prolactin synthesis and trophoblastic differentiation in metastatic choriocarcinoma in the liver.

“…However, the morphology of cytotrophoblast in normal chorionic villi as well as in the tumor tissue of choriocarcinoma has revealed sparse intracytoplasmic organelles endowed with protein synthesis (13,21). Thus, syncytium is regarded as having the capability of synthsizing peptide hormones as was demonstrated by the authors in hCG-fl by means of the fluorescent antibody technique (6). In this regard, the authors have previously demonstrated that PRL is synthesized in the syncytium in normal chorionic villi.…”

Production and Localization of Human Prolactin in Human Chorionic Tissue and Decidua

“…The authors have another idea of morphological characteristics in relation to the secretion mechanism of proteohormone (5). In this paper, the authors describe the production and localization of prolactin by immunohistological investigations materializing normal human placenta and decidua tissue in early pregnancy.…”