Morphological spectrum of fungal infections: a retrospective study

Muniyappa, Usha; Rakshitha, H B; Jasuja, Avnika; Aneesha, Asok; Sharon, Reginald

doi:10.5455/ijmsph.2016.06122015284

Cited by 4 publications

(9 citation statements)

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“…Invasion of tissues and blood vessel indicates invasive candidiasis and that helps in differentiating from colonization. 1,2,4,5,15 In our study, Mucormycosis was seen in three cases (Picture D). Out of which one case was clinically diagnosed as maxillary carcinoma.…”

Section: Discussionsupporting

confidence: 54%

“…These infections are life-threatening, and occur in various immunocompromised patients. 1,3,5,[11][12][13][14] In phaeohyphomycosis, the cyst wall histopathologically consists of fibro-collagenous tissue and granulomatous inflammation with many giant cells. Fungal elements in the form of yeast-like structures and septated hyphae were found throughout the lesions.…”

Section: Discussionmentioning

confidence: 99%

“…Aspergillosis includes three entities: allergic bronchopulmonary aspergillosis (ABPA),chronic pulmonary aspergillosis /aspergilloma, and invasive or systemic aspergillosis. 2,5,15 In ABPA, the lesions may show granulomatous inflammation, vasculitis, interstitial fibrosis, and microabscesses with scanty hyphae which could represent an invasive aspergillosis. Aspergilloma is a mass of fungal hyphae with a necrotic background.…”

Section: Discussionmentioning

confidence: 99%

“…Mucormycosis is common in immunocompromised patients and occurs rarely in immunocompetent hosts following trauma. 2,4,5,15 We had three cases of Maduramycosis (Picture E) Out of which one case had an unusual presentation in the wrist. Usually mycetoma can be classified as eumycotic and actinomycotic mycetoma.…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, for evaluating tissue invasion and host reaction to the organism's histopathology is mandatory. 4,5 Hence histologic evaluation of tissue sections is a quick and easy way for identifying fungal organisms, and also a strong adjunct to microbiologic culture in diagnosing fungal infections. 1,6 In superficial mycosis usaully there won't be any inflammation.…”

Section: Introductionmentioning

confidence: 99%

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Clinicopathological spectrum of fungal infections in a Tertiary Care Centre

2020

IJPO

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Introduction: Fungal lesions are common in immunocompromised patients like Diabetic Mellitus, patients on anticancer drug and radiotherapy, HIV and transplant recipients. Although tissue culture being the gold standard for diagnosing fungal infections, histopathological examination gives better idea about tissue invasion. Materials and Methods: This study was done over 47 cases for a period of four years. This study was done to analyze the clinicopathological spectrum of fungal infections, morphology and their distribution according to age, sex and site of involvement in histopathological specimens in our hospital setup. Results: In this study, the most common fungal organism was found to be Phaeohypomycosis and most of these cases of phaeohypomycosis presented as ganglion and dermoid cyst .Most common site was foot. Conclusion: In this study we attempted to determine the etiological diagnosis of fungal infections in histopathological specimens received in our department.

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Section: Discussionsupporting

confidence: 54%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Clinicopathological spectrum of fungal infections in a Tertiary Care Centre

2020

IJPO

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Histomorphological spectrum of fungal infections

2019

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Background: Fungal infections have become very common resulting in a wide range of diseases from superficial infections to invasive fungal lesions. These organisms are now capable of affecting not only the immunocompromised patients but also healthy immune-competent individuals. All other non-culture methods except histologic method cannot detect all the types of fungi and are not available widely especially in developing countries like India.Methods: This retrospective study conducted in the department of Pathology for a period of 5 years. A total of 29 cases were studied. The aim of this study was to detect the type of fungal infections and their distribution according to age, sex, and organ involvement in histopathologic specimens received in our department.Results: Twenty-nine cases with fungal infections were studied. Of these (22; 75.8%) were males, (7; 24.1%) were females with male dominance. The cases displayed extensive range of age prevalence between 12 and 77 years. The most common type of fungal infection encountered in this study was mucormycosis. The most common site involved in infection was maxillary sinus. Maxillary sinus was the most common site for mucormycosis.Conclusions: The histopathologic examination can provide a swift provisional identification of infectious fungal organisms and remains the only existing reliable means to identify certain pathogens.

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Detección y genotipificación de Pneumocystis jirovecii en muestras de pacientes mexicanos VIH positivos y negativos

Alcántara-Mojica

Delhaès²,

Ramírez-Corona

et al. 2019

GMM

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Pneumocystis jirovecii es un hongo atípico detectado particularmente en pacientes VIH-positivos o con trasplante. Objetivo: Detectar y genotipificar Pneumocystis jirovecii en muestras de pacientes de dos hospitales de la ciudad de México. Método: Fueron procesadas 89 muestras respiratorias, correspondientes a 53 pacientes (30 VIH positivos y 23 VIH negativos) con sintomatología respiratoria y 11 personas sanas incluidas como control negativo. El DNA fue extraído y amplificado por PCR anidada de la región del espaciador transcrito interno, obteniendo un fragmento en cada ronda (de 693 y 550 pb). Los genotipos y su relación filogenética fueron determinados por secuenciación del fragmento de 550 pb. Resultados: Cuarenta y ocho muestras de 30 pacientes VIH-positivos provenían de un solo hospital, de las cuales 11 (36.6 %) fueron positivas a Pneumocystis jirovecii. Ninguna fue positiva en pacientes VIH-negativos o personas sanas. Los haplotipos detectados con mayor frecuencia fueron Eg y Em. Conclusiones: La frecuencia de infección por Pneumocystis jirovecii fue alta en la población mexicana estudiada. El genotipo más frecuente fue diferente a los reportados en otros países. Es necesario encauzar este problema de salud hacia la detección temprana de esta infección.

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Morphological spectrum of fungal infections: a retrospective study

Cited by 4 publications

References 0 publications

Clinicopathological spectrum of fungal infections in a Tertiary Care Centre

Clinicopathological spectrum of fungal infections in a Tertiary Care Centre

Histomorphological spectrum of fungal infections

Detección y genotipificación de Pneumocystis jirovecii en muestras de pacientes mexicanos VIH positivos y negativos

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