Abstract:Introduction. Early diagnosis and prediction of distant metastases in choroidal melanoma patients based on morphological and IHC assessment of the components of the tumor microenvironment is a topical issue. The aim was to evaluate the IHC expression of MMP-9 and type IV collagen in metastatic choroidal melanoma. Materials and methods. We analyzed 43 cases of choroidal melanoma T2(a,b,c)-3N0M0-1 during 2013–2017. The patients were divided into two groups: group 1 included patients with primary choroidal mela… Show more
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