Morphological control and assembly of zinc oxide using a biotemplate

Tomczak, Melanie M.; Gupta, Maneesh K.; Drummy, Lawrence F.; Rozenzhak, Sophie M.; Naik, Rajesh R.

doi:10.1016/j.actbio.2008.11.011

Cited by 98 publications

(129 citation statements)

References 29 publications

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“…The interactions were studied in aqueous media as in the synthesis studies. 1,6,8 Further information in support of the choice of media for ITC experiments is given in S1 of supporting information (SI). ITC experiments were designed to; (i) monitor heat effects of interaction between ZnO and the ZnO-BPs and identify the driving forces of interaction, (ii) determine if alanine mutants of G-12 had different thermodynamic signatures in their adsorption process compared to the original sequence, (iii) determine if differences in adsorption characteristics could be detected for different peptides with a single crystal morphology and an individual peptide with different crystal morphologies and (iv) possibly identify a direct link between thermodynamic changes that occur at the peptide-inorganic interface and the observed peptide directed structural modifications of ZnO.…”

Section: Resultsmentioning

confidence: 99%

“…8 ZnO particles were synthesized following a method using Zn(NO3)2·6H2O and HMTA to form elongated twinned rods and a modification of the method incorporating GT-16 peptide to form lower aspect ratio ZnO twinned platelets. 1,6,8 Synthesized ZnO particles had been characterized using several techniques; scanning electron microscopy (JEOL JSM-840A SEM), Energy dispersive X-ray (EDX) analysis, X-ray diffraction (X'Pert PRO XRD), Fourier transform infrared spectroscopy (Nicolet Magna IR-750), and Thermogramietric analysis (Mettler Toledo TGA/SDTA 851e). 8 Herein, additional characterization of the ZnO particles was carried out before ITC experiments.…”

Section: Methodsmentioning

confidence: 99%

“…8 The peptides used in the study were PD identified G-12 (GLHVMHKVAPPR) peptide, its derivative GT-16 (GLHVMHKVAPPR-GGGC) and alanine mutants of the G-12 peptide. 1,8 The mutants were selected on the basis of peptide stability calculated in silico i.e., molecular dynamics (MD) simulations were used to monitor the conformation and stability of mutants generated by single point substitution of alanine into each position in G-12 sequence. 8 The mutants selected were G-12A6 (GLHVMAKVAPPR) and G-12A11 (GLHVMHKVAPAR), determined to be more stable than G-12 peptide and G-12A12 (GLHVMHKVAPPA) found to be the most unstable sequence generated in solvated and non-solvated states.…”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3][4][5][6][7][8][9][10][11] Peptides have also been shown to act as stabilizers, reducing agents, catalysts or inhibitors when incorporated in solution syntheses of inorganic materials. 10,12,13 Great prospects lie in the use of material binding peptides to improve artificial material formation processes following more environmentally sustainable bioinspired methods.…”

Section: Introductionmentioning

confidence: 99%

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Thermodynamic Study of Interactions Between ZnO and ZnO Binding Peptides Using Isothermal Titration Calorimetry

Limo

Perry

2015

Langmuir

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Whilst material specific peptide binding sequences have been identified using a combination of combinatorial methods and computational modelling tools, a deep molecular level understanding of the fundamental principles through which these interactions occur and in some instances modify the morphology of inorganic materials is far from being fully realized. Understanding the thermodynamic changes that occur during peptide-inorganic interactions and correlating these to structural modifications of the inorganic materials could be the key to achieving and mastering control over material formation processes. This study is a detailed investigation applying isothermal titration calorimetry (ITC) to directly probe thermodynamic changes that occur during interaction of ZnO binding peptides (ZnO-BPs) and ZnO. The ZnO-BPs used are reported sequences G-12 (GLHVMHKVAPPR), GT-16 (GLHVMHKVAPPR-GGGC) and alanine mutants of G-12 (G-12A6, G-12A11 and G-12A12) whose interaction with ZnO during solution synthesis studies have been extensively investigated. The interactions of the ZnO-BPs with ZnO yielded biphasic isotherms comprising both an endothermic and an exothermic event. Qualitative differences were observed in the isothermal profiles of the different peptides and ZnO particles studied. Measured ∆G values were between -6 and -8.5 kcal/mol and high adsorption affinity values indicated the occurrence of favourable ZnO-BP-ZnO interactions. ITC has great potential in its use to understand peptide-inorganic interactions and with continued development, the knowledge gained may be instrumental for simplification of selection processes of organic molecules for the advancement of material synthesis and design.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Thermodynamic Study of Interactions Between ZnO and ZnO Binding Peptides Using Isothermal Titration Calorimetry

Limo

Perry

2015

Langmuir

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“…The most commonly used approach is that involving SDAs ranging from simple molecules, such as amines [13][14][15][16] and anionic species, [17][18][19][20][21] to polymers (DBCP, [22][23][24][25][26][27][28][29] PVP, [30][31][32][33][34][35][36][37][38][39][40][41][42] PAM, 29 and PAH 43 ) and biomolecules. [44][45][46][47][48][49][50][51][52] The SDAs have been shown to affect the morphology of ZnO by imposition of effects on nucleation and/or growth of the crystals. Among these SDAs, biomolecules have received little attention in ZnO synthesis because of their complexity, high cost, and sensitivity to reaction conditions.…”

Section: Introductionmentioning

confidence: 99%

Direct evidence of ZnO morphology modification via the selective adsorption of ZnO-binding peptides

et al. 2011

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Biomolecule-mediated ZnO synthesis has great potential for the tailoring of ZnO morphology for specific application in biosensors, window materials for display and solar cells, dye-sensitized solar cells (DSSCs), biomedical materials, and photocatalysts due to its specificity and multi-functionality. In this contribution, the effect of a ZnO-binding peptide (ZnO-BP, G-12: GLHVMHKVAPPR) and its GGGC-tagged derivative (GT-16: GLHVMHKVAPPRGGGC) on the growth of ZnO crystals expressing morphologies dependent on the relative growth rates of (0001) and (10 10) planes of ZnO have been studied. The amount of peptide adsorbed was determined by a depletion method using oriented ZnO films grown by Atomic Layer Deposition (ALD), while the adsorption behavior of G-12 and GT-16 was investigated using XPS and a computational approach. Direct evidence was obtained to show that (i) both the ZnO-BP identified by phage display and its GGGC derivative (GT-16) are able to bind to ZnO and modify crystal growth in a molecule and concentration dependent fashion, (ii) plane selectivity for interaction with the (0001) versus the (10 10) crystal planes is greater for GT-16 than G-12; and (iii) specific peptide residues interact with the crystal surface albeit in the presence of charge compensating anions. To our knowledge, this is the first study to provide unambiguous and direct quantitative experimental evidence of the modification of ZnO morphology via (selective and nonselective) adsorption-growth inhibition mechanisms mediated by a ZnO-BP identified from phage display libraries.

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Biomineralization

2013

Bio‐Nanomaterials

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Morphological control and assembly of zinc oxide using a biotemplate

Cited by 98 publications

References 29 publications

Thermodynamic Study of Interactions Between ZnO and ZnO Binding Peptides Using Isothermal Titration Calorimetry

Thermodynamic Study of Interactions Between ZnO and ZnO Binding Peptides Using Isothermal Titration Calorimetry

Direct evidence of ZnO morphology modification via the selective adsorption of ZnO-binding peptides

Biomineralization

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