Morphological changes in the retinal pigment epithelium on spectral-domain OCT in the unaffected eyes with idiopathic central serous chorioretinopathy

Gupta, Pranay; Gupta, Vishali; Dogra, Mangat R; Singh, Ramandeep; Gupta, Amod

doi:10.1007/s10792-009-9302-2

Cited by 68 publications

(36 citation statements)

References 28 publications

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“…However, it has been reported in an en face OCT study that it was detected in 35 % of the eyes with acute CSCR [19]. Additionally, RPE layer mapping study using OCT demonstrated that RPE bulging was in 94% of asymptomatic eyes in patients with CSR [25]. RPE bulging was observed in all of the females and a percent of 87.5 in males in our study.…”

Section: Discussioncontrasting

confidence: 55%

Comparison of optical coherence tomography findings in males and females with acute central serous chorioretinopathy

Karanfil¹

2017

New Front Ophthalmol

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Objective: To compare the optical coherence tomography (OCT) findings in males and females with acute central serous chorioretinopathy (CSCR). Materials and methods:In this retrospective study, the OCT scans of 8 females (Group 1) and 16 males (Group 2) cases with acute CSCR which were diagnosed based on clinical, ophthalmological and OCT findings and which was followed in our hospital were retrospectively reviewed. The existence of the OCT findings and patterns regarding CSCR and sub-foveal choroidal thicknesses (SFCTs) were compared.Results: Serous macula detachment (SMD) was present in all of the female and male cases. The most common OCT finding was the brush-border pattern (6 cases, 75%) except SMD and retina pigment epithelium (RPE) bulging in females, and RPE bulging (14 cases, 87.5%) except SMD in males. There was no statistically significant difference in the frequency of OCT findings and patterns between both groups (p>0.05). The mean SFCTs of the eyes with CSCR in Group 1 and Group 2 were 346.08±32.1 µm (ranged from 338 to 365 µm) and 351.32±36.5 µm (ranged from 344 to 376 µm), respectively. The difference between SFCTs in the affected eyes was also not statistically significant (p>0.05).

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Section: Discussioncontrasting

confidence: 55%

Comparison of optical coherence tomography findings in males and females with acute central serous chorioretinopathy

Karanfil¹

2017

New Front Ophthalmol

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“…In the setting of unilateral classic CSC, other authors have alluded to similar forme fruste findings without serous neurosensory detachment in the fellow eye, including pigmentary changes, 17 asymptomatic PEDs, 18,19 choroidal hyperpermeability, vascular dilation, and increased choroidal thickness. 3,5 These reports suggest the presence of a limited CSC variant that may or may not precede the development of the serous macular detachment of classic CSC.…”

Section: Discussionmentioning

confidence: 99%

Pachychoroid Pigment Epitheliopathy

Warrow

Hoang

Freund

2013

Retina

453

332

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Pachychoroid pigment epitheliopathy falls within a spectrum of diseases associated with choroidal thickening that includes central serous chorioretinopathy and polypoidal choroidal vasculopathy, and it should be suspected in eyes with a characteristic fundus appearance related to choroidal thickening and associated retinal pigment epithelial abnormalities but no history of subretinal fluid. Enhanced depth imaging optical coherence tomography confirming an abnormally thick choroid and characteristic retinal pigment epithelial changes on fundus autofluorescence support the diagnosis. Because these patients are frequently misdiagnosed, the recognition of pachychoroid pigment epitheliopathy may avoid unnecessary diagnostic testing and interventions.

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“…Using Fourier domain OCT, Fujimoto et al [8] demonstrated an RPE defect within the PED at a leakage site through which fluid might escape from the sub-RPE space into the subretinal space [8]. In the series described by Gupta et al [26], 94% of the CSR patients showed evidence of RPE bumps and 11.8% had PEDs [26]. …”

Section: Discussionmentioning

confidence: 99%

Quantitative and Qualitative Spectral Domain Optical Coherence Tomography Analysis of Subretinal Deposits in Patients with Acute Central Serous Retinopathy

et al. 2013

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Purpose: To perform qualitative and quantitative analyses of subretinal protein deposits (PDs), seen in acute central serous retinopathy (CSR) patients, using high-resolution spectral domain optical coherence tomography (SD-OCT), in order to investigate whether the present PDs have any significant impact on best corrected visual acuity (BCVA). Methods: Patients diagnosed with acute CSR were included. Using SD-OCT, the following distances/heights were measured: central total retinal thickness, central neurosensory retinal thickness, the vertical and horizontal length of subfoveal subretinal fluid and subfoveal thickness of the PD layer, if present and could be measured. Results: Thirty-eight patients with acute CSR were included. A significant correlation was found between the subfoveal thickness of the PD layer and baseline/final visual acuities in the eyes (r = 0.60, p ≤ 0.001 and r = 0.45, p = 0.008, respectively). Conclusions: The thickness of subfoveal PDs at baseline appears to be an important parameter related to the BCVA and time of CSR resolution.

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Morphological changes in the retinal pigment epithelium on spectral-domain OCT in the unaffected eyes with idiopathic central serous chorioretinopathy

Abstract: Spectral-domain optical coherence tomography showed morphologic alterations in retinal pigment epithelium in both eyes of patients with idiopathic central serous chorioretinopathy.

Cited by 68 publications

References 28 publications

Comparison of optical coherence tomography findings in males and females with acute central serous chorioretinopathy

Comparison of optical coherence tomography findings in males and females with acute central serous chorioretinopathy

Pachychoroid Pigment Epitheliopathy

Quantitative and Qualitative Spectral Domain Optical Coherence Tomography Analysis of Subretinal Deposits in Patients with Acute Central Serous Retinopathy

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