Morphological and Functional Outcome after Brilliant Blue G-Assisted Macular Hole Surgery

Lüke, Julia; Lüdeke, Inger; Acksteiner, Alina; Nassar, Khaled; Hoerauf, Hans; Grisanti, Salvatore; Lüke, Matthias

doi:10.1159/000351658

Cited by 4 publications

(2 citation statements)

References 33 publications

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“…Brilliant Blue G (BBG), also known as acid blue 90 or Coomassie BBG, was first reported in vitreoretinal surgery by Enaida et al and has been used specifically for the staining of the ILM [ 132 ] with good morphological and functional results [ 133 – 135 ]. The dye stains badly the ERM, but some authors performed double BBG staining and double peeling for both ERM and ILM in order to prevent ERM recurrence [ 136 ].…”

Section: Other Dyesmentioning

confidence: 99%

Complications of Macular Peeling

Durán

Manzano-Muñoz

Vallejo-Garcia

et al. 2015

Journal of Ophthalmology

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Macular peeling refers to the surgical technique for the removal of preretinal tissue or the internal limiting membrane (ILM) in the macula for several retinal disorders, ranging from epiretinal membranes (primary or secondary to diabetic retinopathy, retinal detachment…) to full-thickness macular holes, macular edema, foveal retinoschisis, and others. The technique has evolved in the last two decades, and the different instrumentations and adjuncts have progressively advanced turning into a safer, easier, and more useful tool for the vitreoretinal surgeon. Here, we describe the main milestones of macular peeling, drawing attention to its associated complications.

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Section: Other Dyesmentioning

confidence: 99%

Complications of Macular Peeling

Durán

Manzano-Muñoz

Vallejo-Garcia

et al. 2015

Journal of Ophthalmology

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“…After 3 months, the mean BCVA increased not significantly to 0.4 (0.54 ± 0.30), but a significant improvement to 0.2 log MAR units (0.28 ± 0.23) could be detected after 6 months compared to baseline (p < 0.01). 23 …”

Section: Discussionmentioning

confidence: 99%

Visual and anatomical outcome of macular hole surgery at a tertiary healthcare facility

2017

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Objective:To assess visual and anatomical outcome of full thickness macular hole (FTMH) surgery with ILM peeling using brilliant blue G dye.Methods:Thirty patients who had clinically evident macular hole were selected. Pre-operative Optical Coherence Tomography (OCT) was done. In all cases vitrectomy was performed via 23guage 3 ports pars plana (3PPV) vitrectomy system and Brilliant blue G dye, 0.5ml dye was injected over macula which resulted in light blue stain of ILM and peeling was performed around hole in circular motion and after gas fluid exchange gas tamponade with SF6 was done. Final visual and anatomical outcome was measured as postoperative BCVA and postoperative OCT at three months respectively. Descriptive statistics were computed. Paired t-test was applied. P value≤0.05 were considered as significant.Results:There were 12 male and 18 female patients. The mean age was 57.40±4.76 years. The mean size of macular hole was 452.20±242.33μm. The mean duration of symptoms was 16.73±13.49 weeks. Mean pre operative BCVA was 1.30±0.73 log MAR and post operative was 0.51±0.23 log MAR. Mean increased BCVA was found to be 0.22±0.13 log MAR. Primary closure of hole was achieved in 29(96.7%). Significant mean difference was found in pre operative and post operative BCVA.Conclusion:Brilliant blue G exhibits sufficient staining qualities and safety profile to peel ILM in the management of full thickness macular hole with significant visual and anatomical improvement.

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