Morphological and electrophysiological characteristics of layer V neurons of the rat medial entorhinal cortex

Hamam, Bassam; Kennedy, Timothy E.; Alonso, Ángel; Amaral, David G.

doi:10.1002/(sici)1096-9861(20000320)418:4<457::aid-cne7>3.0.co;2-l

Cited by 86 publications

(35 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The pyramidal cells of mammals have one dominant large apical dendrite that often branches close to the soma, whereas the basal dendrites extend extensively in all directions within the deep layers. The apical dendrites and the axon collaterals extend towards the superficial layers, sometimes even reaching the pial surface (Hamam et al 2000(Hamam et al , 2002Canto et al 2008). A major afferent pathway to the mammalian hippocampus comes from the entorhinal cortex (Rosene and Van Hoesen 1987).…”

Section: Discussionmentioning

confidence: 99%

“…A major afferent pathway to the mammalian hippocampus comes from the entorhinal cortex (Rosene and Van Hoesen 1987). The projection from the corticoid complex to the HCC in birds (Casini et al 1986) might originate from CI pyramidal neurons, which can be compared with the projections of the entorhinal cortex to the various parts of hippocampus in mammals Klink and Alonso 1997a;Gloveli et al 1997Gloveli et al , 2001Hamam et al 2000Hamam et al , 2002Fig. 6 Camera lucida drawing of a neuron of the CI: a multipolar neuron with a large soma, spinous dendrites (d), an axon (arrow) and axon collaterals (c).…”

Section: Discussionmentioning

confidence: 99%

“…The polymorphic multipolar neurons of the entorhinal cortex of mammals have medium-sized somata with spherical to slightly pyramidal shape. These neurons have multipolar spiny dendritic arborizations that extend for a long distance in all directions, instead of having dominant apical dendrites (Hamam et al 2000(Hamam et al , 2002Gloveli et al 2001;Canto et al 2008). The spinous multipolar neurons of the corticoid complex of the strawberry finch resemble the medium-sized polymorphic multipolar neurons of the mammalian entorhinal cortex.…”

Section: Discussionmentioning

confidence: 99%

“…These cells show a resemblance to the horizontal cells of the CI in the zebra finch (Montagnese et al 1996) but are not observed in the CI of the strawberry finch. In the entorhinal cortex of mammals, horizontal neurons have been reported that are characterized by sparsely spiny apical dendrites extending to the pial surface and slightly spiny basal dendritic plexus that extend horizontally, whereas their axon travels up to the angular bundle (Lorente de Nó 1933;Lingenhohl and Finch 1991;Hamam et al 2000Hamam et al , 2002Canto et al 2006). These horizontal neurons of the mammalian entorhinal cortex are comparable with the horizontal cells of the CDL region of E. amandava.…”

Section: Bar 50 μMmentioning

confidence: 99%

See 3 more Smart Citations

Neuronal classes in the corticoid complex of the telencephalon of the strawberry finch, Estrilda amandava

2009

View full text Add to dashboard Cite

The present study, based on neurohistological techniques (Nissl-staining, Golgi-impregnation), focuses on the cytoarchitecture of the corticoid complex in the strawberry finch, Estrilda amandava. This complex in birds occupies the dorsolateral surface of the telencephalic pallium and remains subdivided into an intermediate corticoid area (CI) and a dorsolateral corticoid area (CDL). The CDL in the strawberry finch is a thin superficial part of the caudal pallium adjoining the medially situated hippocampal formation, whereas the CI is demarcated between the CDL and the parahippocampal area of telencephalon. Neurons of the corticoid complex are classified into three main cell groups: predominant projection neurons, local circuit neurons and stellate neurons. The spinous projection neurons send out distant projecting axons that typically extend several varicose collaterals. Most of these collaterals lie parallel to the ventricle. These neurons are subclassified into pyramidal neurons (localized only in the CI) and multipolar neurons (present in both the CI and CDL). The CDL also possesses small and medium-sized horizontal cells, which are bitufted or multipolar with smooth, moderately branching dendrites. The aspinous local circuit neurons extend short axons that ramify locally. Stellate neurons have sparse spinous dendrites and locally arborizing axons. The corticoid complex of birds corresponds to the lateral cerebral cortex of lizards and to the entorhinal cortex of mammals on the basis of neuronal morphology and bidirectional connections between adjacent areas.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Bar 50 μMmentioning

confidence: 99%

See 2 more Smart Citations

Neuronal classes in the corticoid complex of the telencephalon of the strawberry finch, Estrilda amandava

2009

View full text Add to dashboard Cite

show abstract

“…According to the Golgi-based description of Lorente de Nó and more recent in vitro intracellular filling studies, layer V contains three classes of principle neurons: pyramidal, horizontal, and (polymorphic) multipolar neurons (Hamam et al, 2000;Gloveli et al, 2001;Wouterlood, 2002;van Haeften et al, 2003).…”

Section: Ec Layer Vmentioning

confidence: 99%

Hippocampal Formation

Cappaert

Strien

Witter

2015

The Rat Nervous System

118

View full text Add to dashboard Cite

Morphological and electrophysiological characteristics of layer V neurons of the rat lateral entorhinal cortex

Hamam

Amaral

Alonso

2002

J of Comparative Neurology

Self Cite

View full text Add to dashboard Cite

The intrinsic electrophysiological and morphological properties of lateral entorhinal area (LEA) layer V neurons were investigated by sharp electrode intracellular recording and biocytin labeling in vitro. The morphological analysis revealed that layer V of the LEA contains three distinct subtypes of principal neurons, which were classified as pyramidal, horizontal, and polymorphic neurons. Pyramidal cells were the most abundant subtype (57%) and could be further subdivided into neurons with large, small, and star-like somas. Similarly to pyramidal cells, horizontal neurons (11%) had a prominent apical dendrite. However, their distinctive basal dendritic plexus extended primarily in the horizontal plane. Polymorphic neurons (32%) were characterized by a multipolar dendritic organization. Electrophysiological analysis of neurons in the three categories demonstrated a diversity of electrophysiological profiles within each category and no significant differences between groups. Neurons in the three subgroups could display instantaneous and/or time-dependent inward rectification and different degrees of spike frequency adaptation. None of the recorded cells displayed an intrinsic oscillatory bursting discharge. Many neurons in the three subgroups, however, displayed slow (3.5-14 Hz), sustained, subthreshold membrane potential oscillations. The morphological and electrophysiological diversity of principal neurons in the LEA parallels that previously reported for the medial entorhinal area and suggests that, with respect to the deep layers, similar information processing is performed across the mediolateral extent of the entorhinal cortex. Layer V of the entorhinal cortex may undertake very complex operations beyond acting as a relay station of hippocampal processed information to the neocortex.

show abstract

Morphological and electrophysiological characteristics of layer V neurons of the rat medial entorhinal cortex

Cited by 86 publications

References 63 publications

Neuronal classes in the corticoid complex of the telencephalon of the strawberry finch, Estrilda amandava

Neuronal classes in the corticoid complex of the telencephalon of the strawberry finch, Estrilda amandava

Hippocampal Formation

Morphological and electrophysiological characteristics of layer V neurons of the rat lateral entorhinal cortex

Contact Info

Product

Resources

About