Morphogenesis of asymmetry of rat brain nuclei under normal conditions and during exposure to microgravitation

Proshchina, Alexandra; Besova, N. V.; Voronov, K. A.; Gulimova, V. I.; Serova, L V; Savel’ev, S. V.

doi:10.1007/bf02682267

Cited by 4 publications

(10 citation statements)

References 3 publications

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“…Proshchina and Savel'ev (1998) showed that in R. temporaria the right brain hemisphere had a larger volume of grey matter, but this asymmetry disappears between the stages 27-36 (Dabagyan & Sleptsova, 1975). It is known that a significant preference to turn to the right in a T-maze exists in rats and mice only during a certain period of life, namely between 11 and 19 months after birth (Obukhova , Klimenko, & Solov'eva, 1997;Solov'eva & Obukhova, 2001).…”

Section: Turning Bias In Tadpoles and Behavioural Asymmetries In Adultsmentioning

confidence: 93%

“…Nevertheless a few examples can be considered. Proshchina and Savel'ev (1998) studied turning behaviour of tadpoles and found no turning preference in B. bufo when they swam out of a T-maze in a current of water. These data do not make a bridge between the behavioural handedness in adult B. bufo (Bisazza et al, 1996(Bisazza et al, , 1997 and its tadpoles (Proshchina & Savel'ev, 1998).…”

Section: Turning Bias In Tadpoles and Behavioural Asymmetries In Adultsmentioning

confidence: 99%

“…The functions of the habenular are uncertain and relationships unequivocally linking this asymmetry to functional asymmetries (e.g., visual) of the amphibian brain or to motor hand preference Dill, 1977;Proshchina & Savel'ev, 1998) are unknown. However, habenular nuclei asymmetry most probably is related to situs viscerum (Stark & von Kraft, 1993).…”

Section: Malashichevmentioning

confidence: 99%

“…In the last five years amphibians have increasingly been the subject of studies on asymmetric morphological traits and lateralised behaviour (Bisazza, Cantalupo, Robins, Rogers, & Vallortigara, 1996;Borkhvardt & Malashichev, 1997Goree & Wassersug, 2001;Malashichev & Nikitina, 2002;Oseen, Newhook, & Wassersug, 2001;Proshchina & Savel'ev, 1998;Yamashita, Naitoh, & Wassersug, 2000). This review mostly covers morphological and motor asymmetries in anuran amphibians with focus on the cause-and-effect relationships of morphological and behavioural traits.…”

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confidence: 98%

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Asymmetries in amphibians: A review of morphology and behaviour

Malashichev

2002

Laterality: Asymmetries of Body, Brain and Cognition

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Morphological and behavioural asymmetries in amphibians are reviewed. Among the characteristics considered are: (1) the asymmetry of the shoulder girdle (epicoracoid overlap); (2) the distribution of the left and right variants of its structure in amphibian populations; (3) asymmetry in the position of the spiracle(s); (4) asymmetric order of forelimb emergence from opercular chambers in tadpoles; and (5) preferential forelimb use in adult amphibians. I show that there are no direct cause-and-effect relationships between these characteristics, which would explain their development. Other asymmetries, such as asymmetry of the visceral organs, turning behaviour of tadpoles, asymmetries in the length and weights of the long bones, and some neuromorphological traits, also show few examples of relationships. However, the simultaneous absence of many asymmetries in some amphibians and their presence in others suggests a common cause, which affects all of these asymmetries indirectly, presumably very early in ontogenesis.

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Section: Turning Bias In Tadpoles and Behavioural Asymmetries In Adultsmentioning

confidence: 93%

Section: Turning Bias In Tadpoles and Behavioural Asymmetries In Adultsmentioning

confidence: 99%

Section: Malashichevmentioning

confidence: 99%

mentioning

confidence: 98%

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Asymmetries in amphibians: A review of morphology and behaviour

Malashichev

2002

Laterality: Asymmetries of Body, Brain and Cognition

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“…According to published data, alterations in many gene activation and gene pathway changes and those associated with the influence of spaceflight conditions have been identified [57]. Moreover, microgravity, and possibly other nonspecific effects of spaceflight, can alter normal brain development [58]. There are also data showing that space-relevant radiation may induce changes in neuronal functions.…”

Section: Gecko Brain In Prolonged Spaceflight Experimentsmentioning

confidence: 99%

Reptiles in Space Missions: Results and Perspectives

Gulimova

Proshchina

Kharlamova

et al. 2019

IJMS

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Reptiles are a rare model object for space research. However, some reptile species demonstrate effective adaptation to spaceflight conditions. The main scope of this review is a comparative analysis of reptile experimental exposure in weightlessness, demonstrating the advantages and shortcomings of this model. The description of the known reptile experiments using turtles and geckos in the space and parabolic flight experiments is provided. Behavior, skeletal bones (morphology, histology, and X-ray microtomography), internal organs, and the nervous system (morphology, histology, and immunohistochemistry) are studied in the spaceflight experiments to date, while molecular and physiological results are restricted. Therefore, the results are discussed in the scope of molecular data collected from mammalian (mainly rodents) specimens and cell cultures in the parabolic and orbital flights and simulated microgravity. The published data are compared with the results of the gecko model studies after the 12–44.5-day spaceflights with special reference to the unique peculiarities of the gecko model for the orbital experiments. The complex study of thick-toed geckos after three spaceflights, in which all geckos survived and demonstrated effective adaptation to spaceflight conditions, was performed. However, future investigations are needed to study molecular mechanisms of gecko adaptation in space.

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Mammalian Development in Space

Ronca

2003

Developmental Biology Research in Space

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Morphogenesis of asymmetry of rat brain nuclei under normal conditions and during exposure to microgravitation

Abstract: Histological and morphometrical analysis of the brain and peripheral analyzers revealed proliferative migration abnormalities of brain development and neuron differentiation in mammals during a space flight, which can limit space exploration.

Cited by 4 publications

References 3 publications

Asymmetries in amphibians: A review of morphology and behaviour

Asymmetries in amphibians: A review of morphology and behaviour

Reptiles in Space Missions: Results and Perspectives

Mammalian Development in Space

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