Morganella morganii, a non-negligent opportunistic pathogen

Liu, Hui; Zhu, Jing; Hu, Qiwen; Rao, Xiancai

doi:10.1016/j.ijid.2016.07.006

Cited by 195 publications

(226 citation statements)

References 119 publications

(110 reference statements)

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“…Generally Morganellamorganii can act as an opportunistic pathogen that mainly causes wound and urinary tract infections. The drug resistance of Morganellamorganii is increasing in recent years, which often results in Clinical treatment failure (Hui Liu et al, 2016). In the present study Morganellamorganii showed highest prevalent (18.52%) in all the analysed seafoods.…”

Section: Results and Discussion:-supporting

confidence: 51%

Isolation of Enterobacteriaceae From Raw Seafoods Sold in Fish Markets in Eastern Province of Saudi Arabia.

MohamedIbrahimM.¹,

Shabeeb²,

Ramadhan³

et al. 2017

IJAR

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Section: Results and Discussion:-supporting

confidence: 51%

Isolation of Enterobacteriaceae From Raw Seafoods Sold in Fish Markets in Eastern Province of Saudi Arabia.

MohamedIbrahimM.¹,

Shabeeb²,

Ramadhan³

et al. 2017

IJAR

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“…Morganella morganii is an unusual opportunistic pathogen that primarily causes post-operative wound and urinary tract infections (Liu et al 2016). Based on histopathology and extensive diagnostic tests, no …”

Section: Discussionmentioning

confidence: 99%

“…This species is considered an unusual opportunistic pathogen that primarily causes post-operative wound and urinary tract infections (Liu et al 2016). Infection with M. morganii can result in various clinical presentations including sepsis, abscessation, purple urine bag syndrome, cho rioamnionitis, and cellulitis in humans.…”

Section: Infectionmentioning

confidence: 99%

Fatal fibrino-hemorrhagic bronchopneumonia associated with Morganella morganii in a bottlenose dolphin: a case report

Elfadl¹,

Lee²,

Kim³

et al. 2017

Dis. Aquat. Org.

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A 5 yr old, 184 kg, and 262 cm total length female bottlenose dolphin Tursiops truncatus was found dead in a display after bloody discharge from the blowhole was observed 3 h prior to death. Pathological examination revealed fibrinous bronchopneumonia with prominent areas of necrosis (sequestra) and numerous Gram-negative bacilli within alveoli and in blood vessels of the lungs and liver and between muscle fibers. The cause of death was attributed to septicemia. Often, cases of fibrinous bronchopneumonia are characterized by bacteremia in the latter stages of infection, resulting in the death of the animal. Septicemia likely accounts for the ecchymoses and petechiae noted on the spleen, pancreas, forestomach, lungs, visceral peritoneum, and small intestine. Additional lesions included hemothorax, stable red frothy fluid in the trachea, and lymphoid depletion in the spleen and lymph nodes. Pure growth of Morganella morganii was isolated from the lungs, blood, liver, and blowhole mucosa. Sequencing of 16s rRNA of the isolated bacteria showed more than 99.6% identity with M. morganii strain FDAARGOS_172. To our knowledge, this is the first report of fatal fibrinonecrotizing bronchopneumonia associated with M. morganii infection in a cetacean.KEY WORDS: Gram-negative bacilli · 16s RNA · Lungs · Sequestra · Hemothorax Resale or republication not permitted without written consent of the publisherDis Aquat Org 127: [41][42][43][44][45][46][47] 2017 ( Thornton et al. 1998). It is also considered a possible cause of swollen head syndrome in broiler chickens in Japan (Tanaka et al. 1995). Respiratory infections associated with this bacterium have been described in piglets (Ono et al. 2001), a jaguar (Choi et al. 2002), a guinea pig (Vandenberge et al. 2013), and a rabbit (Roels et al. 2007). CLINICAL HISTORYA 5 yr old juvenile female bottlenose dolphin Tursiops truncatus with a body weight of 184 kg and a total length of 262 cm was transported from Japan to a new aquarium in South Korea. The dolphin was transferred by car from Wakayama to the port of Osaka, Japan (6 h journey including waiting time in the port), then ferried to Busan, Korea (19 h journey). Finally, the animal was transported to Ulsan Dolphinarium by car (3 h journey).Three months later the animal acutely developed signs of anorexia, slight fever, and abnormal vertical movement in the pool. Bloody discharge from the mouth and blowhole as well as bloody feces were observed 6 h prior to death. Fluids (0.9% NaCl 1000 ml, intraveneous [IV]) were administered with antibiotics, including enrofloxacin 900 mg (intramuscular [IM]), gentamicin 720 mg (IM), cefazolin 3500 mg (IV), and cimetidine 1000 mg (IV). MATERIALS AND METHODS Necropsy and histopathologyA full necropsy was performed 19 h after death, and representative samples from multiple organs were fixed in 10% neutral formalin and submitted for histopathological examination. An additional set of tissues were sampled and individually labeled for ancillary diagnostic studies. Slides were prepared ...

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“…C. freundii is known to cause opportunistic infections such as severe diarrhoea, urinary tract infections, pneumonia and brain abscesses (Badger et al 1999). Besides, several opportunistic human infections caused by bacteria such as E. tarda, M. morganii and P. aeruginosa have been reported (Nelson et al 2009;Bradbury et al 2010;Liu et al 2016).…”

mentioning

confidence: 99%

Comparative in vitro efficacy of eight essential oils as antibacterial agents against pathogenic bacteria isolated from pet-turtles

Silva¹,

Hossain²,

Wimalasena³

et al. 2018

Vet. Med. - Czech

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Essential oils are plant extracts that have been used for their antimicrobial properties for centuries. The keeping of turtles as pets exhibits a growing trend worldwide but these animals are known to harbour a range of pathogenic bacteria. In the current study, we assessed eight essential oils as alternative antibacterial agents against nine species of pet turtle-borne Gram-negative bacteria, namely Aeromonas caviae, A. dhakensis, A. hydrophila, Citrobacter freundii, Morganella morganii, Proteus mirabilis, P. vulgaris, Pseudomonas aeruginosa and Salmonella enterica. Except for Pseudomonas aeruginosa, all other bacterial species showed high susceptibility to six essential oils, namely oregano, cinnamon, clove, lemongrass, lavender and eucalyptus oils in descending order of efficacy. Minimum inhibitory concentrations and minimum bactericidal concentrations values of the essential oils against all tested species except for P. aeruginosa showed low heterogeneity, showing that these essential oils can effectively control the growth of nearly all the tested. However, most of the tested bacteria were multiple-antibiotic-resistant as determined in the antibiotic disc diffusion test, with multiple-antibiotic-resistant index values of ≥ 0.2 for most of the strains. Therefore, with regards to their in vitro activity in controlling growth of multi-drug resistant bacteria, we can classify oregano, cinnamon, clove, lemongrass, lavender and eucalyptus essential oils as effective antibacterial agents. Thus, prospective application of these essential oils in controlling and treating these bacteria should be considered.

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Morganella morganii, a non-negligent opportunistic pathogen

Cited by 195 publications

References 119 publications

Isolation of Enterobacteriaceae From Raw Seafoods Sold in Fish Markets in Eastern Province of Saudi Arabia.

Isolation of Enterobacteriaceae From Raw Seafoods Sold in Fish Markets in Eastern Province of Saudi Arabia.

Fatal fibrino-hemorrhagic bronchopneumonia associated with Morganella morganii in a bottlenose dolphin: a case report

Comparative in vitro efficacy of eight essential oils as antibacterial agents against pathogenic bacteria isolated from pet-turtles

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