More than the SRY: The Non-Coding Landscape of the Y Chromosome and Its Importance in Human Disease
Emily S. Westemeier-Rice,
Michael T. Winters,
Travis W. Rawson
et al.
Abstract:Historically, the Y chromosome has presented challenges to classical methodology and philosophy of understanding the differences between males and females. A genetic unsolved puzzle, the Y chromosome was the last chromosome to be fully sequenced. With the advent of the Human Genome Project came a realization that the human genome is more than just genes encoding proteins, and an entire universe of RNA was discovered. This dark matter of biology and the black box surrounding the Y chromosome have collided over … Show more
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