More than half of adolescent E-Cigarette users had never smoked a cigarette: findings from a study of school children in the UK

Fulton, Emily; Gokal, Kajal; Griffiths, Sarah; Wild, Susan

doi:10.1016/j.puhe.2018.04.014

Cited by 25 publications

(27 citation statements)

References 6 publications

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“…Evidence suggests that ENDS are being used in cessation attempts (Kalkhoran and Glantz 2016;Mantey et al 2017;Weaver et al 2018) as well as by people who choose to continue their nicotine habit either for potential / perceived health benefits (Spears et al 2018;Stokes et al 2018) or social acceptability (Berg et al 2014;Romijnders et al 2018) compared with tobacco smoking. Widespread availability of such devices, particularly with adolescent age ranges, sparks concern that ENDS may facilitate the development of nicotine dependence without any prior use of combustible tobacco products (Fulton et al 2018;Martinasek et al 2018) and may even increase the odds of later initiation of combustible tobacco use (East et al 2018;Loukas et al 2018;Primack et al 2018), a relationship that may be mediated by the nicotine content in the e-cigarettes (Goldenson et al 2017).…”

Section: Introductionmentioning

confidence: 99%

Effects of Nicotine and THC Vapor Inhalation Administered by An Electronic Nicotine Delivery System (ENDS) in Male Rats

Javadi‐Paydar

Cole

Taffe

2018

Preprint

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Background: Electronic nicotine delivery systems (ENDS, e-cigarettes) are increasingly used for the self-administration of nicotine by various human populations, including previously nonsmoking adolescents. Studies in preclinical models are necessary to evaluate health impacts of ENDS including the development of nicotine addiction, effects of ENDS vehicles, flavorants and co-administered psychoactive substances such as ∆ 9 -tetrahydrocannabinol (THC). This study was conducted to validate a rat model useful for the study of nicotine effects delivered by inhalation of vapor created by ENDS.Methods: Male Sprague-Dawley rats (N=8) were prepared with radiotelemetry devices for the reporting of temperature and activity. Experiments subjected rats to inhalation of vapor generated by an electronic nicotine delivery system (ENDS) adapted for rodents. Inhalation conditions included vapor generated by the propylene glycol (PG) vehicle, Nicotine (1, 10, 30 mg/mL in the PG) and THC (12.5, 25 mg/mL). Results: Nicotine inhalation increased spontaneous locomotion and decreased body temperature of rats.Pretreatment with the nicotinic cholinergic receptor antagonist mecamylamine (2 mg/kg, i.p.) prevented stimulant effects of nicotine vapor inhalation and attenuated the hypothermic response. Combined inhalation of nicotine and THC resulted in apparently independent effects which were either additive (hypothermia) or opposed (activity). Conclusions:These studies provide evidence that ENDS delivery of nicotine via inhalation results in nicotine-typical effects on spontaneous locomotion and thermoregulation in male rats. Effects were blocked by a nicotinic antagonist, demonstrating mechanistic specificity. This system will therefore support additional studies of the contribution of atomizer/wick design, vehicle constituents and/or flavorants to the effects of nicotine administered by ENDS.

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Section: Introductionmentioning

confidence: 99%

Effects of Nicotine and THC Vapor Inhalation Administered by An Electronic Nicotine Delivery System (ENDS) in Male Rats

Javadi‐Paydar

Cole

Taffe

2018

Preprint

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“…In 2018 an estimated 2291 adolescents in Great Britain (GB) aged 11-18 years used e-cigarettes (2). Although some reports suggest that regular use (once a week or more) amongst youth is rare and largely limited to current or previous smokers (2)(3)(4), awareness of and experimentation with e-cigarettes is rising (2,(5)(6)(7)(8). Similar trends have been noted in other countries including the USA and Canada (9,10).…”

Section: Introductionmentioning

confidence: 79%

“…This small scale mixed method study aimed to explore Welsh primary schoolchildren's (aged [7][8][9][10][11] awareness of e-cigarettes relative to tobacco smoking, their understanding of the risks and benefits associated with e-cigarettes and their intentions and beliefs about vaping; to inform development of effective prevention strategies and policy responses around e-cigarette use.…”

Section: Introductionmentioning

confidence: 99%

“…be a 'safer option' could be at risk of later tobacco use(8) health promotion efforts need to reframe children's perceptions of e-cigarettes, reinforcing the message that vaping is 'less harmful' rather than 'healthier' and highlighting the associated risks of e-cigarette experimentation including the potential for tobacco initiation.Relative to smoking, most children had little or no understanding of e-cigarette health harms with over half associating vaping with the same health consequences as smoking. Whilst not unexpected given the children's developmental ages, it does reflect a wider trend(52).…”

mentioning

confidence: 99%

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Welsh primary schoolchildren’s perceptions of e-cigarettes: a mixed method study

Porcellato¹,

Houle-Ross²,

Quigg³

et al. 2020

Preprint

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Background: There are concerns that the growing popularity of e-cigarettes promotes experimentation among children. Current research has focused almost exclusively on children over 11 years. Given the possible lifelong health harms caused by behaviours established in early childhood, understanding younger children’s perceptions is essential; to inform tobacco control policies, prevention strategies and the wider debate on further regulation of vaping. In one of the first global studies to provide insights into younger children’s perceptions of e-cigarettes, we explored Welsh primary schoolchildren’s (aged 7-11) awareness of e-cigarettes relative to tobacco smoking, their understanding of the risks and benefits associated with e-cigarettes and their intentions and beliefs about vaping. Methods: Data was collected using a mix of methods in June and July 2017 from 8 purposively selected primary schools across Wales. Four hundred and ninety-five children (52% female), aged 7 years (n=165), 9 years (n=185) and 11 years (n=145) completed a class-administered booklet encompassing a draw and write exercise and questionnaire. Ninety-six children participated in 24 peer cohort-based discussion groups comprised of 2 boys and 2 girls. Data from the three tools were analysed independently and findings triangulated. Questionnaire analyses used frequencies, descriptive statistics and chi-squared tests. Content analysis was undertaken on the draw and write data and peer discussion groups were analysed thematically. Results: Primary schoolchildren have general awareness of e-cigarettes but understanding of any health harms or the role of nicotine in e-cigarettes is poor or misperceived, particularly in the youngest children. Vaping was viewed as healthier than smoking by most and there was some recognition that e-cigarettes were used for smoking cessation. Few children intended to smoke (1.8%) or vape (3.9%) in the future but almost half thought it was okay for grownups. Children’s perceptions were influenced by exposure through family and friends. Conclusions: There is a need for e-cigarette education in primary schools. Health promotion efforts should reinforce the message that vaping is ‘less harmful’ rather than ‘healthier’ and highlight associated risks of e-cigarette experimentation including the potential for tobacco initiation. Further research is needed to explore whether children’s perceptions influence their future use of tobacco or e-cigarettes.

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“…We are of course happy if e-cigarette use in teenagers in the UK predominantly occurs in those who already smoke although we note that the number of vaping teenagers has tripled in the last 5 years (14) and that a school-based study from UK found that more than half of e-cigarette users had never used tobacco (15). Among US e-cigarette users aged 18-24 years in 2015, 40.0% had never been regular cigarette smokers (14).…”

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confidence: 94%

A rational approach to e-cigarettes: challenging ERS policy on tobacco harm reduction

Pisinger

Vestbo

2020

Eur Respir J

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More than half of adolescent E-Cigarette users had never smoked a cigarette: findings from a study of school children in the UK

Cited by 25 publications

References 6 publications

Effects of Nicotine and THC Vapor Inhalation Administered by An Electronic Nicotine Delivery System (ENDS) in Male Rats

Effects of Nicotine and THC Vapor Inhalation Administered by An Electronic Nicotine Delivery System (ENDS) in Male Rats

Welsh primary schoolchildren’s perceptions of e-cigarettes: a mixed method study

A rational approach to e-cigarettes: challenging ERS policy on tobacco harm reduction

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