More than a third of middle-aged adults (50–65) have understated executive dysfunction

Segaux, Lauriane; Oubaya, Nadia; Leissing-Desprez, Claire; Langavant, Laurent Cléret de; Broussier, Amaury; Naga, Henri; Fromentin, Isabelle; David, Jean‐Philippe; Bastuji‐Garin, Sylvie

doi:10.1080/13607863.2022.2046696

Cited by 1 publication

(2 citation statements)

References 33 publications

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“…The main issue seems to be adherence to long-term treatment, and a study done by our group almost a decade ago showed poor compliance to drugs that have the potential to slow cognitive decline or prevent dementia, even among those who received the medicines for free [13]. Consider that studies have shown that incipient cognitive impairment may be common [1,14].…”

Section: Treating Cardiovascular Risk Factors Associated With Cogniti...mentioning

confidence: 99%

“…Identifying cognitive impairment in those with cardiovascular risk is important and several scales have been described for the same. The clock-drawing test may be valuable for identifying high-risk individuals who may then benefit from targeted non-pharmacological prevention (Mediterranean diet, exercise, cognitive training, and vascular risk factor management) [14]. Community education is an essential part of re-integrating the patient into the social setting.…”

Section: Non-pharmacological Preventionmentioning

confidence: 99%

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Cardiovascular Comorbidities and Cognitive Impairment

Dhikav¹,

Kumar²,

Anand³

2022

OBM Geriatr

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Various grades of cognitive impairment generally occur in older adults over the age of 55, where cardiovascular risk factors such as diabetes and/or hypertension, coronary artery disease, or cerebrovascular accidents are also common. Cognitive impairment occurs in various forms, from mild or amnesia such as forgetting today's date to more ominous and progressive forms, such as frank dementia. Over 5 million people worldwide suffer from dementia, most of whom live in low- and middle-income countries. It has been envisaged from the beginning that dementia or cognitive impairment has neurodegenerative origins. However, recent studies have indicated that dementia may have a mixed origin or may be preceded by vascular insult and then neurodegenerative pathology. From a pathophysiological standpoint, one of the puzzling questions in the field of cognitive impairment and comorbidities is that it is not clear whether cardiovascular comorbidity or cognitive impairment comes first. Cognitive impairment negatively affects mobility and fitness and this can potentially contribute to development of hypertension or/and diabetes. The present review examines this perplexing situation and tries to anser whether the comorbid conditions are innocent bystanders to cognitive impairment or they play greater causative roles. The rationale of the review is that it is possible to address these cardiovascular risk factors for dementia prevention and hence it summarizes the evidence related to cardiovascular risk factors and cognitive impairment.

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Section: Treating Cardiovascular Risk Factors Associated With Cogniti...mentioning

confidence: 99%

Section: Non-pharmacological Preventionmentioning

confidence: 99%