Morbihan Syndrome

Suzuki, Mikiya; Watari, Takashi

doi:10.1007/s11606-022-07858-x

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2023

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“…A review of the literature was undertaken by searching PubMed using the keywords "Morbihan disease", "highintensity ultrasound", "micro-focused ultrasound", and "macro-focused ultrasound", and revealed several Morbihan disease cases that were effectively treated with systemic therapy and surgical excision from 2004 to 2022 (Table 1), while no energy-based treatment has been reported to be effective. [4][5][6][7][8][9][10][11][12][13][14][15][16][17]…”

Section: Literature Reviewmentioning

confidence: 99%

Effect of High-Intensity Macro-Focused Ultrasound on a Case of Morbihan Disease

Li¹,

Meng²,

Zhang³

et al. 2023

CCID

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Morbihan disease is a rare entity involving the upper two-thirds of the face and characterized by chronic erythematous edema, which is recalcitrant to the traditional therapy of rosacea. We report a case of Morbihan disease effectively treated with macro-focused high-intensity focus ultrasound (MF-HIFU). After MF-HIFU treatment, an obvious reduction in swelling was observed with decreased erythema and hyperalgesia. In addition, in-vitro experiments were conducted to measure the actual temperature of the skin tissue under the epidermis. The results of the in-vitro experiments showed that the temperature plateau in the skin sample was reached at approximately 42°C after 5-min treatment or longer. MF-HIFU might be a promising energy-based therapy for Morbihan disease.

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