Morbidity, mortality and economic burden of renal impairment in cardiac intensive care

Chew, Derek P.; Astley, Carolyn; Molloy, D.; Vaile, J.; Pasquale, Carmine G. De; Aylward, P. E.

doi:10.1111/j.1445-5994.2006.01012.x

Cited by 22 publications

(13 citation statements)

References 28 publications

(29 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This iatrogenic complication has been a subject of concern to physicians in recent years because of its adverse effect on prognosis and addition to healthcare costs. At the same time, many hospitalized patients have compromised renal function [4, 5] which is the most important risk factor for contrast-induced AKI. This paper highlights conclusions from the Contrast-Induced Nephropathy (CIN) Consensus Working Panel, an international multidisciplinary group convened to address the challenges of contrast-induced AKI whose findings were published in 2006 [6,7,8,9,10,11,12].…”

Section: Introductionmentioning

confidence: 99%

Radiocontrast-Induced Acute Kidney Injury

McCullough¹

2008

Nephron Physiol

View full text Add to dashboard Cite

Many radiographic studies and procedures use iodinated contrast media and consequently pose the risk of contrast-induced acute kidney injury (AKI). This is an important complication, which accounts for a significant number of cases of hospital-acquired renal failure associated increased hospital length of stay and increased mortality. Sustained reductions in renal blood flow, hypoxic injury, direct cellular toxicity by the contrast media, and superimposed organ injury are all believed to play a role in this form of AKI. Avoidance of dehydration and multimodality prevention measures may reduce rates of this problem in patients at risk. Contrast-induced AKI is likely to remain a significant challenge for specialists in the future since the patient population is aging, chronic kidney disease and diabetes are coming more common, and use of iodinated contrast is growing.

show abstract

Section: Introductionmentioning

confidence: 99%

Radiocontrast-Induced Acute Kidney Injury

McCullough¹

2008

Nephron Physiol

View full text Add to dashboard Cite

show abstract

“…Patients with pre-existing renal disease, diabetes, congestive heart failure or older age are at the greatest risk in developing CIN [16][17][18]. These high-risk patients have a calculated incidence of CIN ranging from 10% to 30% [4,[18][19][20].…”

mentioning

confidence: 99%

Impact of biplane versus single-plane imaging on radiation dose, contrast load and procedural time in coronary angioplasty

Sadick¹,

Reed²,

Collins³

et al. 2010

BJR

View full text Add to dashboard Cite

ABSTRACT. Coronary angioplasties can be performed with either single-plane or biplane imaging techniques. The aim of this study was to determine whether biplane imaging, in comparison to single-plane imaging, reduces radiation dose and contrast load and shortens procedural time during (i) primary and elective coronary angioplasty procedures, (ii) angioplasty to the main vascular territories and (iii) procedures performed by operators with various levels of experience. This prospective observational study included a total of 504 primary and elective single-vessel coronary angioplasty procedures utilising either biplane or single-plane imaging. Radiographic and clinical parameters were collected from clinical reports and examination protocols. Radiation dose was measured by a dose-area-product (DAP) meter intrinsic to the angiography system. Our results showed that biplane imaging delivered a significantly greater radiation dose (181.4¡121.0 Gycm 2 ) than single-plane imaging (133.6¡92.8 Gycm 2 , p,0.0001). The difference was independent of case type (primary or elective) (p50.862), vascular territory (p50.519) and operator experience (p50.903). No significant difference was found in contrast load between biplane (166.8¡62.9 ml) and single-plane imaging (176.8¡66.0 ml) (p50.302). This non-significant difference was independent of case type (p50.551), vascular territory (p50.308) and operator experience (p50.304). Procedures performed with biplane imaging were significantly longer (55.3¡27.8 min) than those with single-plane (48.9¡24.2 min, p50.010) and, similarly, were not dependent on case type (p50.226), vascular territory (p50.642) or operator experience (p50.094). Biplane imaging resulted in a greater radiation dose and a longer procedural time and delivered a non-significant reduction in contrast load than single-plane imaging. These findings did not support the commonly perceived advantages of using biplane imaging in single-vessel coronary interventional procedures.

show abstract

“…At the same time, critically ill patients are likely to have compromised renal function and are often elderly. 92 Contrast medium-induced nephropathy (CIN) is a serious complication; it is associated with increases in hospital length of stay, requirement for dialysis, and risk for death. 15,93 CIN is defined as an increase in serum creatinine that occurs within the first 24 hours after exposure to contrast medium and peaks within 3 days after the exposure.…”

mentioning

confidence: 99%

Acute Kidney Injury: Not Just Acute Renal Failure Anymore?

Dirkes

2011

Critical Care Nurse

View full text Add to dashboard Cite

Until recently, no uniform standard existed for diagnosing and classifying acute renal failure. To clarify diagnosis, the Acute Dialysis Quality Initiative group stated its consensus on the need for a clear definition and classification system of renal dysfunction with measurable criteria. Today the term acute kidney injury has replaced the term acute renal failure, with an understanding that such injury is a common clinical problem in critically ill patients and typically is predictive of an increase in morbidity and mortality. A classification system, known as RIFLE (risk of injury, injury, failure, loss of function, and end-stage renal failure), includes specific goals for preventing acute kidney injury: adequate hydration, maintenance of renal perfusion, limiting exposure to nephrotoxins, drug protective strategies, and the use of renal replacement therapies that reduce renal injury.

show abstract

Morbidity, mortality and economic burden of renal impairment in cardiac intensive care

Cited by 22 publications

References 28 publications

Radiocontrast-Induced Acute Kidney Injury

Radiocontrast-Induced Acute Kidney Injury

Impact of biplane versus single-plane imaging on radiation dose, contrast load and procedural time in coronary angioplasty

Acute Kidney Injury: Not Just Acute Renal Failure Anymore?

Contact Info

Product

Resources

About