Morbidity and Mortality Outcome in Late Preterm Neonates at a Tertiary Care Hospital

Amin, Tahsinul; Nur, Ayesha Najma

doi:10.3329/jafmc.v12i1.39966

Cited by 4 publications

(4 citation statements)

References 3 publications

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“…The ndings indicate that nearly a quarter (23.8%) of preterm infants and only 4.1% of term infants died during the neonatal period. A similar mortality rate of 28% for preterm and 6% for term infants was reported in a study conducted in Bangladesh 11 . Contrary, a lower mortality rate among preterm infants was reported in high-income countries like Australia (7.7%) and the USA (1.4%) 12,13 .…”

Section: Discussionsupporting

confidence: 84%

Comparison of Common Adverse Neonatal Outcomes Among Preterm and Term Infants at the National Referral Hospital in Tanzania: A Case-Control Study

Rugumisa

Sangeda

Bongcam‐Rudloff

et al. 2021

Preprint

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BackgroundThe first month of life is the most critical in a child’s heath because it is associated with the highest risk of adverse health outcomes. In Tanzania the risk of adverse health outcomes in preterm infants is five times higher compared to term infants.The objective of this study was to assess common adverse health outcomes and compare the risk of such outcomes between preterm and term infants, in Tanzania, within the first 28 days of life.MethodsThis was a case-control study involving preterm (cases) and term (controls) infants delivered at the Muhimbili National Hospital between August and October 2019 . About 222 pairs of cases and controls were reviewed for their medical records. Logistic regression was used to compare the risk of neonatal outcomes between the study groups. Statistical significance was achieved at P-value < 0.05 and 95% confidence interval.ResultsPreterm infants have an increased risk of mortality (OR = 7.2, 95% CI: 3.4-15.1), apnea (OR = 4.7, 95% CI: 3.4-15.1), respiratory distress syndrome (OR = 4.8, 95% CI: 3.2-7.3), necrotizing enterocolitis (OR = 5.5, 95% CI: 1.2-25.3), anemia (OR = 4.3 , 95% CI: 2.8-6.6), pneumonia (OR = 2.7, 95% CI: 1.6-4.6) and sepsis (OR = 2.6, 95% CI: 1.7-3.9) in the first month of life compared to term infants. No differences in the risk of intraventricular hemorrhage, bronchopulmonary dysplasia, patent ductus arteriosus and jaundice were observed between preterm and term infants. ConclusionThe findings of this study informs the Tanzanian health sector about the most common and high risk neonatal outcomes in preterm infants. Additionaly, for promoting neonates' health, the health sector needs to consider preventing and treating the most common and high risk adverse neonatal outcomes in preterm infants.

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Section: Discussionsupporting

confidence: 84%

Comparison of Common Adverse Neonatal Outcomes Among Preterm and Term Infants at the National Referral Hospital in Tanzania: A Case-Control Study

Rugumisa

Sangeda

Bongcam‐Rudloff

et al. 2021

Preprint

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“…This may be due to the fact that KMC service facilitates skin-to-skin contact, optimal breastfeeding, and prevention of apnea and colonization of the neonate's skin with mutualistic maternal skin microbial flora. These clinical significances of KMC help prevent the neonates from being hypothermia, hypoglycemic, distressed, and developing infection thereby increasing their survival ( 33 , 35 , 45 , 49 , 50 ). Therefore, preterm infants whose birth weight is <2,000 g and have relatively stable vital signs should always receive KMC service to optimize their survival.…”

Section: Discussionmentioning

confidence: 99%

Predictors of Survival Among Preterm Neonates Admitted to Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia

et al. 2022

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BackgroundPre-maturity is the primary cause of neonatal mortality in the world. Although prematurity was the leading cause of neonatal mortality, the survival rate and its predictors may be varied from setting to setting and time to time due to different reasons. Therefore, this study aimed to assess the survival probability and predictors of mortality among preterm neonates at Felege Hiwot comprehensive specialized hospital.MethodsThis is a retrospective follow-up study that included 542 randomly selected preterm neonates admitted at Felege Hiwot comprehensive specialized hospital from the period of 2016-2020. Semi-parametric and parametric survival models were fitted to identify the survival probability of preterm neonates and its association with different predictors. The best fit model was selected using Akaike's information criteria, Bayesian information criteria and likelihood ratio criteria.ResultsThe cumulative incidence and incidence rate of mortality among preterm neonates were 31 per 100 live births and 3.5 per 100 neonate days, respectively. From the adjusted cox-proportional-hazard model, predictors with higher preterm mortality risk include the presence of neonatal respiratory distress syndrome [AHR = 2.55, 95% CI: 1.23; 3.74], perinatal asphyxia [AHR = 4.26, 95% CI: 1.35; 6.79] and jaundice [AHR = 3.25, 95% CI: 2.14, 7.24]. However, admission weight of 1,500–2,499 g (AHR = 0.23, 95% CI: 0.11, 0.56) and ≥2,500 g (AHR = 0.12, 95% CI: 0.02; 0.32), early breastfeeding [AHR = 0.44, 95% CI: 0.36; 0.48] and kangaroo mother care [AHR = 0.11, 95% CI: 0.03; 0.15] were protective factors of preterm mortality.ConclusionThe cumulative incidence of mortality among preterm neonates was consistent with the national incidence of preterm mortality. Factors such as respiratory distress syndrome, perinatal asphyxia, breastfeeding, kangaroo mother care, admission weight, and jaundice are significant predictors of survival. Therefore, considerable attention such as intensive phototherapy, optimal calorie feeding, oxygenation, and good thermal care should be given for admitted preterm neonates.

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“…The present study shows that the proportion of preterm infants with neonatal morbidity was nearly twice that of term infants (84.9% vs. 43.3%). In a study conducted in Bangladesh, similar proportions were observed, whereby 76% of preterm and 28% of term infants had morbidities 11 . The most common morbidities among preterm infants were RDS (75.2%) and apnea (72.3%).…”

Section: Baseline Neonatal Characteristics Are Presented In Tablementioning

confidence: 62%

“…The risk of overall morbidity was also higher in preterm infants than term infants by seven-folds. infants was reported in a study conducted in Bangladesh 11 . Contrary, a lower mortality rate among preterm infants was reported in high-income countries like Australia (7.7%) and the USA (1.4%) 12,13 .…”

Section: Baseline Neonatal Characteristics Are Presented In Tablementioning

confidence: 86%

Comparison of common adverse neonatal outcomes among preterm and term infants at the National Referral Hospital in Tanzania: a case-control study

Rugumisa¹,

Sangeda²,

Bongcam‐Rudloff³

et al. 2022

Ethiop. j. pediatr. child health

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Background: Neonatal period is a critical period in a child’s heath because it is associated with higher risk of adverse health outcomes. The objective of this study was to assess common adverse health outcomes and compare the risk of such outcomes between preterm and term neonates, in Tanzania. Methods: This was a case-control study involving infants admitted at Muhimbili National Hospital between August and October 2020. About 222 pairs of preterm and term infants were followed until discharge. Logistic regression was used to compare risk of health outcomes. Statistical significance was achieved at p–value < 0.05 and 95% confidence interval. Result: Preterm neonates had increased risk of mortality (OR = 7.2, 95% CI: 3.4-15.1), apnea (OR = 4.7, 95% CI: 3.4 – 15.1), respiratory distress syndrome (OR = 10.9, 95% CI: 6.1 – 19.6), necrotizing enterocolitis (OR = 5.5, 95% CI: 1.2 – 25.3), anemia (OR = 4.3, 95% CI: 2.8 – 6.6), pneumonia (OR = 2.7, 95% CI: 1.6 – 4.6) and sepsis (OR = 2.6, 95% CI: 1.7 – 3.9). No difference in risk of intraventricular hemorrhage, patent ductus arteriosus and jaundice was observed. Conclusion: For promoting neonates' health, prevention and treatment of the higher risk adverse neonatal outcomes should be prioritized.

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Morbidity and Mortality Outcome in Late Preterm Neonates at a Tertiary Care Hospital

Cited by 4 publications

References 3 publications

Comparison of Common Adverse Neonatal Outcomes Among Preterm and Term Infants at the National Referral Hospital in Tanzania: A Case-Control Study

Comparison of Common Adverse Neonatal Outcomes Among Preterm and Term Infants at the National Referral Hospital in Tanzania: A Case-Control Study

Predictors of Survival Among Preterm Neonates Admitted to Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia

Comparison of common adverse neonatal outcomes among preterm and term infants at the National Referral Hospital in Tanzania: a case-control study

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