Morbidity and mortality in cirrhotic patients undergoing anesthesia and surgery

Outcome analysis of hip or knee arthroplasty in patients with cirrhotic liver disease

“…16 The Mayo Clinic study included 26 patients undergoing combined hip and pelvic surgeries for fractures and the result of perioperative complication rate was reported as 53.8%. 14 The only previously study that exclusively evaluated the safety of hip arthroplasty is a recent uncontrolled study from Taiwan that overall perioperative complication rate was 26.7%. 17 The previously published data on the outcome of TKA in cirrhotic patients were included 41 Child's A cirrhotic patients and only 1 Child's B patient from a recent study in Taiwan.…”

Systemic abnormalities in liver disease

“…In contrast, surgery on patients with chronic hepatitis can generally be considered safe [210] , and there have been no deaths or complications reported in patients with chronic hepatitis C undergoing laparoscopic cholecystectomy [211] . In patients with liver cirrhosis, complications and mortality rates of surgery are high [212] , especially if one or more of the following factors apply to the patient: elevated bilirubin, prolonged PT, ascites, decreased albumin, encephalopathy, portal hypertension, elevated creatinine concentration, intraoperative hypotension and emergent surgery [213] . The outcome of surgery also depends on the invasiveness or duration of the operation [214] .…”

Increased Rates of Periprosthetic Joint Infection in Patients With Cirrhosis Undergoing Total Joint Arthroplasty

“…This at-risk age group is also the primary group of patients who may elect to undergo total joint replacements during the next few decades. Patients with cirrhosis are at greater risk for surgical complications [31], partly owing to immune dysfunction [3,22]. However, there has been little research on patients with cirrhosis undergoing orthopaedic procedures.…”