Morbidity after elective resection of prenatally diagnosed asymptomatic congenital pulmonary airway malformations

Hall, Nigel; Chiu, Priscilla; Langer, Jacob C.

doi:10.1002/ppul.23255

Cited by 35 publications

(12 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Elective surgery is not without risk and postoperative complications occurred in 5% of asymptomatic infants, including air leak, infection, effusion and death in one case 11. Hall et al 44 45 recently reported a complication rate of 23% in a case series of 60 patients with asymptomatic CPAM who underwent surgery. This included complications in three cases defined as major: tension pneumothorax, aggressive chest wall fibromatosis and near fatal haemorrhage.…”

Section: Discussionmentioning

confidence: 99%

The natural history of prenatally diagnosed congenital cystic lung lesions: long-term follow-up of 119 cases

Cook

Chitty²,

Coppi³

et al. 2017

Arch Dis Child

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

The natural history of prenatally diagnosed congenital cystic lung lesions: long-term follow-up of 119 cases

Cook

Chitty²,

Coppi³

et al. 2017

Arch Dis Child

View full text Add to dashboard Cite

show abstract

“…Furthermore, most of these children are now diagnosed prenatally and therefore have clinically relevant data that must be extracted from the maternal medical record prior to analysis [12]. Delivering evidence-based, quality care with complication rates that are as low as possible is especially critical for asymptomatic CLMs given that we, as pediatric surgeons, are asking families to consent to a major operation performed relatively infrequently for an incidentally identified lesion that may or may not cause any problems later in life [13,14].…”

Section: Introductionmentioning

confidence: 99%

Development of a multi-institutional registry for children with operative congenital lung malformations

Kunisaki

Saito

Fallat

et al. 2020

Journal of Pediatric Surgery

View full text Add to dashboard Cite

Introduction: The purpose of this study was to develop a multi-institutional registry to characterize the demographics, management, and outcomes of a contemporary cohort of children undergoing congenital lung malformation (CLM) resection. Methods: After central reliance IRB approval, a web-based, secure database was created to capture retrospective cohort data on pathologically-confirmed CLMs performed between 2009-2015 within a multi-institutional research collaborative. Results: Eleven children's hospitals contributed 506 patients. Among 344 prenatally diagnosed lesions, the congenital pulmonary airway malformation volume ratio was measured in 49.1%, and fetal MRI was performed in 34.3%. One hundred thirty-four (26.7%) children had respiratory symptoms at birth. Fifty-eight (11.6%) underwent neonatal resection, 322 (64.1%) had surgery at 1-12 months, and 122 (24.3%) had operations after 12 mos. The median age at resection was 6.7 months (interquartile range, 3.6-11.4). Among 230 elective lobectomies performed in asymptomatic patients, thoracoscopy was successfully utilized in 102 (44.3%), but there was substantial variation across centers. The most common lesions were congenital pulmonary airway malformation (n=234, 47.3%) and intralobar bronchopulmonary sequestration (n=106, 21.4%). Conclusion: This multicenter cohort study on operative CLMs highlights marked disease heterogeneity and substantial practice variation in preoperative evaluation and operative management. Future registry studies are planned to help establish evidencebased guidelines to optimize the care of these patients.

show abstract

“…[5] Reports of thoracosopic lobectomy for CLM vary and some have described high conversion rates (up to 20%) and significant complications. [6][7][8] The only previous meta-analysis of thoracoscopic and open CLM resection included 216 patients from six reports (all pre-2010), two of which described only four patients in each treatment arm. [9][10][11] Since this report, there has been a large number of highvolume case series of CLM resection.…”

Section: Introductionmentioning

confidence: 99%

Does thoracoscopy have advantages over open surgery for asymptomatic congenital lung malformations? An analysis of 1626 resections

Adams

Jobson

Sangnawakij

et al. 2017

Journal of Pediatric Surgery

View full text Add to dashboard Cite

show abstract

Morbidity after elective resection of prenatally diagnosed asymptomatic congenital pulmonary airway malformations

Abstract: Resection of prenatally diagnosed asymptomatic CPAM is associated with a significant risk of complications, which may be life threatening. These data contribute to a balanced discussion of risks and benefits for these children.

Cited by 35 publications

References 32 publications

The natural history of prenatally diagnosed congenital cystic lung lesions: long-term follow-up of 119 cases

The natural history of prenatally diagnosed congenital cystic lung lesions: long-term follow-up of 119 cases

Development of a multi-institutional registry for children with operative congenital lung malformations

Does thoracoscopy have advantages over open surgery for asymptomatic congenital lung malformations? An analysis of 1626 resections

Contact Info

Product

Resources

About