Moral Issues of Human-Non-Human Primate Neural Grafting

Greene, Mark E.; Schill, Kathryn E.; Takahashi, Shoji X.; Bateman-House, Alison; Beauchamp, Tom L.; Bok, Hilary; Cheney, Dorothy L.; Coyle, Joseph T.; Deacon, Terrence W.; Dennett, Daniel C.; Donovan, Peter; Flanagan, Owen; Goldman, Steven A.; Greely, Henry T.; Martin, Lee J.; Miller, Earl K.; Mueller, Dawn; Siegel, Andrew W.; Solter, Davor; Gearhart, John D.; McKhann, Guy M.; Faden, Ruth R.

doi:10.1126/science.1112207

Cited by 83 publications

(56 citation statements)

References 12 publications

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“…One could envision a black market for embryos derived from this type of "self-fertilization." Controversial experiments, such as grafting human neural precursors derived from iPS cells into nonhuman primates (Greene et al, 2005), would be made easier and more difficult to monitor. Due to these concerns and others, the government of Japan has forbidden the "implantation of embryos made with iPS cells into human or animal wombs, the production of an individual in any other way from iPS cells, the introduction of iPS cells into an embryo or fetus, and the production of germ cells from iPS cells" (Cyranoski, 2008).…”

Section: Biological and Bioethical Issues With Ips Cellsmentioning

confidence: 99%

Stretching the limits: Stem cells in regeneration science

Stocum

Zupanc

2008

Developmental Dynamics

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Section: Biological and Bioethical Issues With Ips Cellsmentioning

confidence: 99%

Stretching the limits: Stem cells in regeneration science

Stocum

Zupanc

2008

Developmental Dynamics

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“…And there's no philosophical consensus on the moral significance of changes in abilities if we could detect them. (Greene, 2005) The organizers of the panel may be commended for initiating this discussion. The fact, however, that 22 so-called experts could not specify what kind of effect implanting human cells might have on non-human primates does not speak particularly well for arguments for the blanket acceptance of this or similar techniques of genetic technologies.…”

Section: The Context Of Genetic Technologiesmentioning

confidence: 99%

Leonardo¿s Choice

Gigliotti¹

2009

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“…[23] Authors who have commented on or contributed to policy debates specify that chimeras which would be so humanlike that they would have an altered moral status and threaten our notion of 'human dignity' are at the forefront of the ethical controversy [24], [25] . If the chimeras were to share the characteristics which are otherwise unique and important to human beings, human dignity would be undermined and the chimeras would be worthy of the same respect that humans are.…”

Section: The Moral Worth Of An Ambiguous Entity: a 'Mind-bending' Conmentioning

confidence: 99%

On the Moral Status of Humanized Chimeras and the Concept of Human Dignity

Ravelingien

Braeckman²,

Legge³

2006

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Recent advances in the technology of creating chimeras have evoked controversy in policy debates. At centre of controversy is the fear that a substantial contribution of human cells or genes in crucial areas of the animal's body may at some point render the animal more humanlike than any other animals we know today. Authors who have commented on or contributed to policy debates specify that chimeras which would be too humanlike would have an altered moral status and threaten our notion of 'human dignity'. This setting offers a productive opportunity to test the notion of human dignity and to emphasize some of its weaknesses as an ethical tool. Limiting chimerism experiments on the basis of whether or not it undermines or challenges human dignity implies a clear demarcation of those characteristics which are typically, and importantly, human. Evidence of our evolutionary ties and behavioral similarities with other animals seem to annul all attempts to define the uniquely human properties to which human dignity may be attributed. Hence, it has been suggested that the particular moral status associated with humans cannot be explained for beyond an intuitive basis. In what follows, we will argue that the difficulties inherent in the notion of human dignity lie not in the impossibility to acquire a list of properties which are unique to humans, but rather in the difficulty to demonstrate the moral relevance of these properties, and particularly the relevance of their being human. We offer an alternative interpretation of the concept of dignity which is not necessarily related to being human.

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Moral Issues of Human-Non-Human Primate Neural Grafting

Cited by 83 publications

References 12 publications

Stretching the limits: Stem cells in regeneration science

Stretching the limits: Stem cells in regeneration science

Leonardo¿s Choice

On the Moral Status of Humanized Chimeras and the Concept of Human Dignity

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