Mooseer (Allium hirtifolium) boosts growth, general health status, and resistance of rainbow trout (Oncorhynchus mykiss) against Streptococcus iniae infection

Rashidian, Ghasem; Mahboub, Heba H.; Fahim, Azin; Hefny, Ahmed A.; Prokić, Marko D.; Rainis, Simona; Boldaji, Javad Tahmasebi; Faggio, Caterina

doi:10.1016/j.fsi.2021.12.012

Cited by 34 publications

(10 citation statements)

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“…To avoid the resistance of the pathogen to antibiotics [ 4 ], plants are a non-antibiotic, safe, and cheap source that exhibits potent antibacterial activity in aquaculture [ 5 , 6 , 7 , 8 ]. Another significant reason for utilizing plant extracts is their natural multi-constituents that are well-documented and verified for promising fish growth and immune-antioxidant traits [ 9 , 10 , 11 ]. In addition, they protect farmed fish exposed to biotic and abiotic stressors [ 12 ], which negatively affect the performance of fish [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Physiological Performance, Antioxidant and Immune Status, Columnaris Resistance, and Growth of Nile Tilapia That Received Alchemilla vulgaris-Supplemented Diets

et al. 2022

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The current perspective is a pioneering trial to assess the efficacy of the dietary supplementation of Alchemilla vulgaris powder (AVP) in the diet of Nile tilapia (Oreochromis niloticus) on growth performance, blood picture, hepatic and renal biomarkers, immune status, and serum and tissue antioxidant capacity and to investigate the resistance against Flavobacterium columnare challenge. Fish (n = 360) were distributed into six groups (three replicates each) and received increasing AVP supplementation levels (0, 2, 4, 6, 8, and 10 g kg−1) for 60 days. Furthermore, fish were exposed to the bacterial challenge of a virulent F. columnare strain and maintained under observation for 12 days. During the observation period, clinical signs and the cumulative mortality percentage were recorded. The results demonstrated that the growth performance, feed conversion ratio, and hematological profile were noticeably enhanced in the AVP-supplemented groups compared to the control. The most promising results of weight gain and feed conversion ratio were recorded in the groups with 6, 8, and 10 g AVP kg−1 diets in a linear regression trend. The levels of hepatorenal function indicators were maintained in a healthy range in the different dietary AVP-supplemented groups. In a dose-dependent manner, fish fed AVP dietary supplements displayed significant augmented serum levels of innate immune indicators (lysozyme, nitric oxide, and complement 3) and antioxidant biomarkers (Catalase (CAT), superoxide dismutase (SOD), total antioxidant (TAC), and reduced glutathione (GSH) with a marked decrease in myeloperoxidase (MPO) and malondialdehyde (MDA) levels). Likewise, hepatic CAT and SOD activities were significantly improved, and the opposite trend was recorded with hepatic MDA. The highest AVP-supplemented dose (10 g/kg) recorded the highest immune-antioxidant status. Based on the study findings, we highlight the efficacy of AVP as a nutraceutical dietary supplementation for aquaculture to enhance growth, physiological performance, and immune-antioxidant status and as a natural economic antibacterial agent in O. niloticus for sustaining aquaculture. It could be concluded that the dietary supplementation of 10 g AVP/kg enhanced O. niloticus growth, physiological performance, immune-antioxidant status, and resistance against F. columnare.

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Section: Introductionmentioning

confidence: 99%

Physiological Performance, Antioxidant and Immune Status, Columnaris Resistance, and Growth of Nile Tilapia That Received Alchemilla vulgaris-Supplemented Diets

et al. 2022

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“…Our findings were supported by Otasevic (2007) who recorded that some species of Cladosporium are pathogenic and toxigenic and are known to produce mycotoxins, cladosporin, emodin (mutagenic and cytotoxic product) and some other toxic compounds. Also, Grinn-Gofroń Malondialdehyde, SOD and CAT are among antioxidants that have been found in large numbers in cells and are responsible for preventing or recovering the damage induced by reactive oxygen species (ROS), thus reflecting the health and physiological status of fish (Mahboub et al, 2022;Rashidian et al, 2022;Weydert & Cullen, 2010). Also, MDA is a vital marker of cell membrane injury (Mir, Qamar, Qadir, Naqvi & Begum, 2020).…”

Section: Discussionmentioning

confidence: 99%

“…Malondialdehyde, SOD and CAT are among antioxidants that have been found in large numbers in cells and are responsible for preventing or recovering the damage induced by reactive oxygen species (ROS), thus reflecting the health and physiological status of fish (Mahboub et al, 2022; Rashidian et al, 2022; Weydert & Cullen, 2010). Also, MDA is a vital marker of cell membrane injury (Mir, Qamar, Qadir, Naqvi & Begum, 2020).…”

Section: Discussionmentioning

confidence: 99%

Detection, diagnosis, Koch’s postulate, hepatorenal and antioxidant indicators for some systemic pathogenic fungi invading the liver and kidneys of African catfish ( Clarias gariepinus ) in Egypt with a histopathological approach

Mahboub

Nada

Abdel‐Ghany

et al. 2022

Aquaculture Research

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Recently, systemic fungal infections have emerged as significant causes of fish morbidity and mortality. Hence, the current study investigates the occurrence of some pathogenic systemic fungi inducing severe lesions in the liver and kidneys of African catfish. Two hundred diseased African catfish were collected from private fish farms in Egypt, and only 120 fish were infected with 212 different fungal isolates at a rate of 60%. The seasonal survey revealed isolation of 72 isolates of yeast (Candida albicans) and 140 isolates of moulds including non‐pigmented moulds, Aspergillus ochraceous and Aspergillus flavus, as well as pigmented mould (Cladosporium herbarum). The isolated fungi induced characteristic post‐mortem lesions. To date, this is the first report for isolation of C. herbarum and C. parapsilosis from Nile catfish liver and kidneys. Various techniques were performed to identify the fungi including gross observation, microscopic examination of tissue squashes, in vitro culture and histopathology. Koch's postulate was fulfilled to confirm the fungal pathogenicity. The challenged fungi altered the hepatorenal indicators (ALP, AST, ALT, urea and creatinine) and oxidative stress biomarkers (MDA, CAT and SOD). The results indicate the virulence of the isolated fungi, and future studies are needed for treatment trials.

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“…Numerous natural products have broad‐spectrum antiviral activity, can inhibit numerous viral infections and replication steps, and have been used to treat SARS, MERS, influenza, and dengue viruses. There have been reports of many chemical structures of bioactive phytomolecules that are beneficial in the management of COVID‐19‐related complications (Panche et al, 2016; Rashidian et al, 2023; Rashidian, Mahboub, et al, 2022; Rashidian, Shahin, et al, 2022). Additionally, medicinal plant‐derived immunomodulators inhibit the inflammatory effect responsible for the substantial morbidity and mortality associated with COVID‐19 infection.…”

Section: Covid‐19 and Medicationmentioning

confidence: 99%

Flavonoids derived from medicinal plants as a COVID‐19 treatment

Sopjani,

Falco,

Impellitteri

et al. 2024

Phytotherapy Research

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The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) causes COVID‐19 disease. Through its viral spike (S) protein, the virus enters and infects epithelial cells by utilizing angiotensin‐converting enzyme 2 as a host cell's receptor protein. The COVID‐19 pandemic had a profound impact on global public health and economies. Although various effective vaccinations and medications are now available to prevent and treat COVID‐19, natural compounds derived from medicinal plants, particularly flavonoids, demonstrated therapeutic potential to treat COVID‐19 disease. Flavonoids exhibit dual antiviral mechanisms: direct interference with viral invasion and inhibition of replication. Specifically, they target key viral molecules, particularly viral proteases, involved in infection. These compounds showcase significant immunomodulatory and anti‐inflammatory properties, effectively inhibiting various inflammatory cytokines. Additionally, emerging evidence supports the potential of flavonoids to mitigate the progression of COVID‐19 in individuals with obesity by positively influencing lipid metabolism. This review aims to elucidate the molecular structure of SARS‐CoV‐2 and the underlying mechanism of action of flavonoids on the virus. This study evaluates the potential anti‐SARS‐CoV‐2 properties exhibited by flavonoid compounds, with a specific interest in their structure and mechanisms of action, as therapeutic applications for the prevention and treatment of COVID‐19. Nevertheless, a significant portion of existing knowledge is based on theoretical frameworks and findings derived from in vitro investigations. Further research is required to better assess the effectiveness of flavonoids in combating SARS‐CoV‐2, with a particular emphasis on in vivo and clinical investigations.

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Mooseer (Allium hirtifolium) boosts growth, general health status, and resistance of rainbow trout (Oncorhynchus mykiss) against Streptococcus iniae infection

Cited by 34 publications

References 34 publications

Physiological Performance, Antioxidant and Immune Status, Columnaris Resistance, and Growth of Nile Tilapia That Received Alchemilla vulgaris-Supplemented Diets

Physiological Performance, Antioxidant and Immune Status, Columnaris Resistance, and Growth of Nile Tilapia That Received Alchemilla vulgaris-Supplemented Diets

Detection, diagnosis, Koch’s postulate, hepatorenal and antioxidant indicators for some systemic pathogenic fungi invading the liver and kidneys of African catfish ( Clarias gariepinus ) in Egypt with a histopathological approach

Flavonoids derived from medicinal plants as a COVID‐19 treatment

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