Mood stabilisation with lamotrigine in rapid cycling bipolar disorder: A double-blind placebo-controlled study

Kusumakar, Vivek; Greene, Paul L.; Earl, N.; Ascher, John; Monaghan, E.; Smoot, Tonya M.; Fouche, Nicki; Bowden, Charles L.; Calabrese, Joseph R.; Post, Robert M.; Sachs, Gary S.; Suppes, Patricia; Gyulai, Laszlo; Young, Thomas J.; Rapaport, M.

doi:10.1016/s0924-977x(00)80179-0

Search citation statements

Order By: Relevance

Paper Sections

Select...

Patient-specific Characteristics1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2004

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a study of acutely manic patients randomly assigned to treatment with divalproex, lithium, or placebo, among the subset of patients who had previously been treated with lithium and then were randomly assigned to lithium, most recent response to lithium when manic was highly associated with response in the study. Among patients who reported a previous good response, the improvement in manic symptoms during the study was 42%, whereas among those who reported previous unsatisfactory response, improvement was only 3% during the trial [14].…”

Section: Patient-specific Characteristicsmentioning

confidence: 86%

Relationship of acute mania symptomatology to maintenance treatment response

Bowden

2004

Curr Psychiatry Rep

View full text Add to dashboard Cite

Most treatment of bipolar disorders addresses maintenance objectives. In the past 4 years, several large, blinded, randomized, placebo-controlled maintenance studies involving more than 3000 patients with bipolar I illness have been published, with analyses of background, symptomatic, and acute treatment factors contributing to maintenance effectiveness. This article summarizes these findings. Generally, indices of greater severity predict lower response rates to most monotherapy treatments. Some findings have been unexpected. Mixed mania did not predict different maintenance response to divalproex or lithium but predicted more side effects with either drug, and reduced efficacy of olanzapine or lamotrigine.

show abstract

Section: Patient-specific Characteristicsmentioning

confidence: 86%

Relationship of acute mania symptomatology to maintenance treatment response

Bowden

2004

Curr Psychiatry Rep

View full text Add to dashboard Cite

show abstract

Mood stabilisation with lamotrigine in rapid cycling bipolar disorder: A double-blind placebo-controlled study

Cited by 1 publication

References 3 publications

Relationship of acute mania symptomatology to maintenance treatment response

Relationship of acute mania symptomatology to maintenance treatment response

Contact Info

Product

Resources

About