Mood and cortisol responses following tryptophan-rich hydrolyzed protein and acute stress in healthy subjects with high and low cognitive reactivity to depression

Firk, Christine; Markus, C. Rob

doi:10.1016/j.clnu.2009.03.002

Cited by 59 publications

(41 citation statements)

References 46 publications

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“…Third, it is suggested that depression-induced stress increases cortisol levels that also increase serotonergic vulnerability. Thus, increasing serotonin through a tryptophan-rich diet has been shown to yield promising effects (Firk & Markus, 2009). Finally, a cognitive explanation for this effect is that mood problems also require cognitive ability to ruminate and dwell on such emotional states; this rumination depletes the cognitive reserves needed to perform other cognitive functions.…”

Section: Other Comorbidities and Related Conditionsmentioning

confidence: 98%

Comorbidities and Cognitive Functioning

Vance

Larsen

Eagerton

et al. 2011

Journal of Neuroscience Nursing

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Optimal cognitive functioning is necessary to successfully negotiate one's environment, yet medical conditions can interfere with brain health, thus negatively impacting cognitive functioning. Such comorbidities include hypertension, heart disease, diabetes, depression, and HIV, as well as others. The physiological properties of these comorbidities can reduce one's cognitive reserve and limit one's cognitive efficiency. This article provides an overview of a few common comorbidities known to affect cognitive functioning and addresses ways in which cognitive functioning may be ameliorated and protected or mitigated in lieu of cognitive declines in such clinical populations. Implications for nursing practice and research are posited.

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Section: Other Comorbidities and Related Conditionsmentioning

confidence: 98%

Comorbidities and Cognitive Functioning

Vance

Larsen

Eagerton

et al. 2011

Journal of Neuroscience Nursing

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“…In humans, positive effects of the augmentation of a tryptophan-rich hydrolyzed protein in the diet on mood under physiological stress have been described [29]. However, the role of tryptophan in the serotonergic system of SAD patients is not clear [30], as is the case with the role of serotonergic systems in the pathogenesis of SAD [31]. The amount of tryptophan in a group of vegetarians was higher than in a group of carnivores, but the relationship between food intake and plasma concentration was questioned [32].…”

Section: Discussionmentioning

confidence: 99%

Is There a Relationship between Vegetarianism and Seasonal Affective Disorder? A Pilot Study

Meesters

Maukonen²,

Partonen³

et al. 2016

Neuropsychobiology

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Background and Aim: Seasonal patterns of food intake are found in healthy individuals and particularly in patients with seasonal affective disorder (SAD). One nutritional choice is a vegetarian diet. Methods: In a Finnish population study, FINRISK 2012, information about diet and SAD was collected. In a Dutch outpatient clinic, SAD patients were asked if they were vegetarian. Results: The percentage of SAD patients among Finnish vegetarians was 4 times higher than in the normal population. The percentage of vegetarians among the SAD patients in a Dutch outpatient clinic was 3 times higher than in the normal population. In the Dutch population, the seasonal loss of energy, in particular, is related to vegetarianism. Conclusion: These findings suggest a possible link between vegetarianism and SAD.

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“…Intake of W has been linked with an increase in serotonin level in the brain of animal 45 and human subjects 41 . Increased serotonin levels in the central nervous system may beneficially 15 modulate stress-related and cognitive function 41,[46][47][48][49] . A significant increase in plasma W:LNAA ratio was seen, which induced anxiolytic-like effects in rats fed with -La enriched whey proteins (190 g kg -1 ).…”

Section: Release Of Free W and W-containing Peptides During The Digesmentioning

confidence: 99%

Milk proteins as a source of tryptophan-containing bioactive peptides

Nongonierma

Fitzgerald

2015

Food Funct.

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Tryptophan (W) is an essential amino acid which is primarily required for protein synthesis. It also acts as 5 a precursor of key biomolecules for human health (serotonin, melatonin, tryptamine, niacin, nicotinamide adenine dinucleotide (NAD), phosphorylated NAD (NADP), quinolinic acid, kynureric acid, etc.). Among dietary proteins, milk proteins are particularly rich in W. W residues within milk proteins may be released by proteolytic/peptidolytic enzymes either as a free amino acid or as part of peptide sequences. Different W-containing peptides originating from milk proteins have been shown in vitro to display a 10 wide range of bioactivities such as angiotensin converting enzyme (ACE) inhibition along with antioxidant, antidiabetic and satiating related properties. Free W has been shown in certain instances to have an effect on cognition and the aforementioned bioactive properties. However, a higher bioactive potency has generally been observed with specific W-containing peptides compared to free W. Since W is thermolabile, the impact of processing on the stability of W-containing peptides needs to be considered. 15Milk protein-derived W-containing peptides may have significant potential as natural health promoting agents in humans.

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Mood and cortisol responses following tryptophan-rich hydrolyzed protein and acute stress in healthy subjects with high and low cognitive reactivity to depression

Cited by 59 publications

References 46 publications

Comorbidities and Cognitive Functioning

Comorbidities and Cognitive Functioning

Is There a Relationship between Vegetarianism and Seasonal Affective Disorder? A Pilot Study

Milk proteins as a source of tryptophan-containing bioactive peptides

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