Montreal Cognitive Assessment (MoCA): Validation Study for Vascular Dementia

Freitas, Sandra; Simões, Mário R.; Alves, Lara Bacelar; Vicente, Margarida; Santana, Isabel

doi:10.1017/s135561771200077x

Cited by 120 publications

(124 citation statements)

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“…De acordo com estes resultados, propuseram dados normativos considerando essas duas variáveis (Anexo 1 -http://www.actamedicaportuguesa.com/revista/ index.php/amp/editor/downloadFile/6889/19736). Paralelamente, o mesmo grupo desenvolveu estudos de validação do MMSE num centro terciário, abrangendo os principais grupos nosológicos de défice cognitivo e demência: défice cognitivo ligeiro (DCL) e doença de Alzheimer (DA), 15 demência frontotemporal (DFT) 16 , demência vascular (DV) 17 e demência com corpos de Lewy (DCLewy). 18 A pontuação de corte mais favorável para o DCL foi o valor de 29, correspondendo-lhe valores de sensibilidade 67%, de especificidade 72% e acuidade diagnóstica de 69%.…”

Section: Introductionunclassified

“…2) avaliar especificamente a validade da última proposta de dados normativos baseados nessas duas variáveis (Freitas et al) 14 ; 3) testar a acuidade diagnóstica das pontuações de corte propostas para a população portuguesa nos estudos de validação para DCL e para as formas mais prevalentes de demência, [15][16][17][18] utilizando novos coortes patológicos mais robustos; 4) partindo desses resultados, propomo-nos analisar o contributo e as limitações do MMSE no diagnóstico hierár-quico do défice cognitivo nos diversos níveis de cuidados de saúde, desde o screening básico de "declínio cognitivo" até ao diagnóstico nosológico mais específico.…”

Section: Introductionunclassified

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Mini-Mental State Examination: Avaliação dos Novos Dados Normativos no Rastreio e Diagnóstico do Défice Cognitivo

et al. 2016

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RESUMOIntrodução: O Mini-Mental State Examination é o teste de rastreio de défice cognitivo/demência mais difundido. No nosso país têm-se utilizado pontuações de corte definidas por grupos de literacia, mas existem novas propostas sustentadas por estudos mais representativos. Propomo-nos confirmar a influência da idade e da escolaridade no desempenho, avaliar a capacidade discriminativa dos novos dados normativos e testar a acuidade diagnóstica das pontuações de corte validadas para o défice cognitivo ligeiro e para as formas mais prevalentes de demência. The Mini-Mental State Examination is the most commonly used cognitive screening test. In Portugal, the cut-off scores are defined according to literacy groups, but different proposals have been recommended by more representative studies. We therefore propose to confirm the influence of demographical variables, such as age and education, in the subject's performance; evaluating the discriminant ability of the new normative data; and to further examine the diagnostic acuity of the validated cut-off scoring for mild cognitive impairment and for the most prevalent types of dementia. Material and Methods: Our study includes 1 441 educated subjects, divided into seven subgroups: Mild cognitive impairment, Alzheimer's disease, frontotemporal dementia, vascular dementia, dementia with Lewy bodies, community-controls and memory cliniccontrols. Results: Altogether age and education explain 10.4% of the Mini-Mental State Examination results variance, with both variables contributing significantly to the results' prediction. The diagnostic acuity based on the most recent normative data was always higher than the one obtained through the validation cut-off scoring, revealing an overall excellent specificity (superior to 90%) and different sensitivity values: excellent for mild Alzheimer's disease (91%), good for dementia with Lewy Bodies (78%) and low for mild cognitive impairment (65%), frontotemporal dementia and vascular dementia (55%). Discussion and Conclusions:The performance on the Mini-Mental State Examination is influenced by age and education, supporting the use of normative data that consider those variables. With this approach, the Mini-Mental State Examination could be a sensitive and specific instrument for the Alzheimer's disease screening among all healthcare levels. Nevertheless, its diagnostic acuity is limited in other conditions frequently seen in memory clinics, such as Mild Cognitive Impairment and other types of dementia.

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Section: Introductionunclassified

Mini-Mental State Examination: Avaliação dos Novos Dados Normativos no Rastreio e Diagnóstico do Défice Cognitivo

et al. 2016

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“…Similar findings were reported in assessment of cognitive impairment in sub-acute stroke; in a community sample of 91 stroke and TIA patients more than 1-year post stroke the MoCA was found to be more sensitive in detecting MCI than the MMSE (Pendlebury et al, 2012b). Additionally the MoCA has also been shown to be a reliable test of VaD above that of the MMSE (Freitas et al, 2012). Freitas et al (2012) compared groups of patients with VaD, Alzheimer's dementia (AD) and healthy adult group.…”

Section: Cognition and Post-stroke Cognitive Impairmentsupporting

confidence: 62%

“…Additionally the MoCA has also been shown to be a reliable test of VaD above that of the MMSE (Freitas et al, 2012). Freitas et al (2012) compared groups of patients with VaD, Alzheimer's dementia (AD) and healthy adult group. They found that the MoCA was able to discriminate between the clinical (AD and VaD) and healthy groups significantly and with greater sensitivity and specificity than the MMSE (Freitas et al, 2012).…”

Section: Cognition and Post-stroke Cognitive Impairmentmentioning

confidence: 99%

Investigating the ability of post-stroke EEG measures of brain dysfuntion to inform early prediction of cognitive impairment or depression outcomes

Schleiger¹

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“…For this reason, it is essential to increase awareness of the general practitioner and their ability to diagnose both early cognitive impairment and depression (17,18). Both the Montreal Cognitive Assessment (MoCA) and the Saint Louis University Mental Status (SLUMS) examination are useful tools for diagnosing MCI (19,20). The Patient Health Questionnaire-9 (PHQ-9) is replacing the Geriatric Depression Scale as the diagnostic test of choice for depression, particularly as the MDS 3.0 has developed a validated version that can be used in cognitively impaired individuals (21,22).…”

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confidence: 99%

Behavioral management in the person with dementia

Morley

2013

The Journal of nutrition, health and aging

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Montreal Cognitive Assessment (MoCA): Validation Study for Vascular Dementia

Cited by 120 publications

References 50 publications

Mini-Mental State Examination: Avaliação dos Novos Dados Normativos no Rastreio e Diagnóstico do Défice Cognitivo

Mini-Mental State Examination: Avaliação dos Novos Dados Normativos no Rastreio e Diagnóstico do Défice Cognitivo

Investigating the ability of post-stroke EEG measures of brain dysfuntion to inform early prediction of cognitive impairment or depression outcomes

Behavioral management in the person with dementia

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