Monte Carlo Simulation of Scatter Field for Calculation of Contrast of Discs in Synthetic CDMAM Images

Díaz, Oliver; Yip, Mary; Cabello, Jorge; Dance, David R.; Young, Kenneth C.; Wells, Kevin

doi:10.1007/978-3-642-13666-5_85

Cited by 8 publications

(10 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The scatter was taken into consideration in the insertion process with the following steps: removal of the estimated local scatter in the clinical image (around the insertion site) to facilitate local adjustment of the primary transmission due to the DLA mass, and then re-instatement of the local scatter 5 (block 5 and 6). The scatter to primary ratio (SPR) was calculated using the validated Monte Carlo model of Diaz et al 14 which is based on the Geant4 toolkit 15 . Finally, the resultant raw mammogram with the inserted mass was processed by the manufacturer's post acquisition image processing package (LORAD FFDM Selenia v 5.0), (block 7).…”

Section: Insertion Of Simulated Masses In 2d Mammogramsmentioning

confidence: 99%

“…The scatter to primary ratio used here was calculated using the validated Monte Carlo Model of Diaz et al 17 for the Hologic Selenia Dimension Tomosynthesis system geometry for a set of breast thicknesses, glandularity and different projection angles. The resulting values were tabulated so that the SPR for any breast thickness, glandularity, and projection angle could be found by interpolation (block 13,14). The manufacturer's reconstruction software was used to reconstruct the tomographic breast image planes from the raw projection images (block 15).…”

Section: Insertion and Reconstructionmentioning

confidence: 99%

See 1 more Smart Citation

Simulation of 3D DLA masses in digital breast tomosynthesis

Rashidnasab

Elangovan

Díaz

et al. 2013

Medical Imaging 2013: Physics of Medical Imaging

Self Cite

View full text Add to dashboard Cite

Digital breast tomosynthesis (DBT) is suggested to have superior performance compared to 2D mammography in terms of cancer visibility, especially in the case of dense breasts. However, the overall performance of tomosynthesis for screening applications, and the manner in which tomosynthesis should be optimally used for screening remains unclear. This motivates the development of software tools that can insert user-defined synthetic pathology of realistic appearance into clinical tomosynthesis images for subsequent use in virtual clinical trials. We present a method for inserting lesions grown using Diffusion Limited Aggregation, previously validated in 2D mammograms, into clinical DBT images. A preliminary pilot study was used to validate the realism of the masses, wherein three readers each viewed 19 cases and rated the realism of the inserted masses. Each case included a simulated mass inserted in the tomosynthesis projections and the counterpart digital 2D mammogram. These results show that masses can be successfully embedded in the tomosynthesis projections and can produce visually authentic DBT images containing synthetic pathology. These results will be used to further optimize the appearance of these masses in DBT for an upcoming validation.

show abstract

Section: Insertion Of Simulated Masses In 2d Mammogramsmentioning

confidence: 99%

Section: Insertion and Reconstructionmentioning

confidence: 99%

Simulation of 3D DLA masses in digital breast tomosynthesis

Rashidnasab

Elangovan

Díaz

et al. 2013

Medical Imaging 2013: Physics of Medical Imaging

Self Cite

View full text Add to dashboard Cite

show abstract

“…10 9 photons emerging from a point source at 66cm from the detector have been used for each simulation, irradiating the entire receptor's dimension. Primary and scattered photons were recorded in a region of interest of area 1cm 2 at 6cm from the chest wall and SPR calculated specifically for this study using the methodology described in [12].…”

Section: Mass Insertion Scatter and Processingmentioning

confidence: 99%

Realistic simulation of breast mass appearance using random walk

et al. 2012

Self Cite

View full text Add to dashboard Cite

The aim of the present work was to develop a method for simulating breast lesions in digital mammographic images. Based on the visual appearance of real masses, three dimensional masses were created using a 3D random walk method where the choice of parameters (number of walks and number of steps) enables one to control the appearance of the simulated structure. This work is the first occasion that the random walk results have been combined with a model of digital mammographic imaging systems. This model takes into account appropriate physical image acquisition processes representing a particular digital X-ray mammography system. The X-ray spectrum, local glandularity above the insertion site and scatter were all taken account during the insertion procedure. A preliminary observer study was used to validate the realism of the masses. Seven expert readers each viewed 60 full field mammograms and rated the realism of the masses they contained. Half of the images contained real, histologically-confirmed masses, and half contained simulated lesions. The ROC analysis of the study (average AUC of 0.58±0.06) suggests that, on the average, there is evidence that the radiologists could distinguish, somewhat, between real and simulated masses.

show abstract

“…Typically, conventional two‐dimensional (2D) mammography employs geometrical rejection (i.e., antiscatter grids) to reduce the amount of scattered radiation arriving at the image receptor. In this modelling situation, for a constant thickness phantom, the use of a uniform scatter signal in the central area of the image can be considered . However, most DBT geometries do not include such geometrical rejection and the scatter variation across the projected breast area should be taken into account .…”

Section: Introductionmentioning

confidence: 99%

Simple method for computing scattered radiation in breast tomosynthesis

et al. 2019

Self Cite

View full text Add to dashboard Cite

Purpose: Virtual clinical trials (VCT) are a powerful imaging tool that can be used to investigate digital breast tomosynthesis (DBT) technology. In this work, a fast and simple method is proposed to estimate the two-dimensional distribution of scattered radiation which is needed when simulating DBT geometries in VCTs. Methods: Monte Carlo simulations are used to precalculate scatter-to-primary ratio (SPR) for a range of low-resolution homogeneous phantoms. The resulting values can be used to estimate the two-dimensional (2D) distribution of scattered radiation arising from inhomogeneous anthropomorphic phantoms used in VCTs. The method has been validated by comparing the values of the scatter thus obtained against the results of direct Monte Carlo simulation for three different types of inhomogeneous anthropomorphic phantoms. Results: Differences between the proposed scatter field estimation method and the ground truth data for the OPTIMAM phantom had an average modulus and standard deviation of over the projected breast area of 2.4 AE 0.9% (minimum À17.0%, maximum 27.7%). The corresponding values for the University of Pennsylvania and Duke University breast phantoms were 1.8 AE 0.1% (minimum À8.7%, maximum 8.0%) and 5.1 AE 0.1% (minimum À16.2%, maximum 7.4%), respectively. Conclusions: The proposed method, which has been validated using three of the most common breast models, is a useful tool for accurately estimating scattered radiation in VCT schemes used to study current designs of DBT system.

show abstract

Monte Carlo Simulation of Scatter Field for Calculation of Contrast of Discs in Synthetic CDMAM Images

Cited by 8 publications

References 8 publications

Simulation of 3D DLA masses in digital breast tomosynthesis

Simulation of 3D DLA masses in digital breast tomosynthesis

Realistic simulation of breast mass appearance using random walk

Simple method for computing scattered radiation in breast tomosynthesis

Contact Info

Product

Resources

About