Monte Carlo optimization method based QSAR modeling of postmortem redistribution of structurally diverse drugs

Abstract

Post-mortem redistribution (PMR) involves a multifaceted process that renders the analytical results of drug concentrations inaccurate for the interpretation of forensic toxicologists. The present study’s aim was to assess whether...

Quantitative Structure–Activity Relationship Models for the Angiotensin-Converting Enzyme Inhibitory Activities of Short-Chain Peptides of Goat Milk Using Quasi-SMILES

“…The main advantage of the Monte Carlo method is the use of randomness to solve problems that, in principle, may be more or less deterministic. Nowadays, computers easily supply randomness to the interested user through random variable generators [50][51][52][53][54][55][56][57][58][59][60]. The models considered are certainly largely random.…”