Monovalent Ion Effect on Liquid–Liquid Phase Separation of Aqueous Polyphosphate–Salt Mixtures
Tomohiro Furuki,
Azusa Togo,
Hatsuho Usuda
et al.
Abstract:Polyphosphate (polyP) is one of the most conserved biomacromolecules and can form aggregates, such as polyP granules in bacteria, which are generated through liquid-liquid phase separation (LLPS). Studies have examined the mechanism of polyP aggregation using LLPS systems containing artificial polyP molecules as aggregation system models, where LLPS is typically induced by multivalent salts and polyelectrolytes. Although the typical concentrations of monovalent ions in living cells are approximately 100 times … Show more
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