Monolayer properties of membrane lipids of the extreme halophile Halobacterium cutirubrum, at the air/water interface

Tomoaia-Cotişel, Maria; Zsakó, J.; Mocanu, Aurora; Chifu, Emil; Quinn, Peter J.

doi:10.1016/0005-2736(88)90031-4

Cited by 13 publications

(8 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It can be seen that the differences between effects of pH and NaCl on Ao only become apparent where pH = 0 = pNaCl. The values for A. appear to be the same, within experimental error, for pH and pNaCl and are consistent with expulsion of electrolytes from the monolayer at pressures approaching collapse of the film (Tomoaia-Cotisel et al, 1988).…”

Section: Methodssupporting

confidence: 71%

Surface characteristics of phosphatidylglycerol phosphate from the extreme halophile Halobacterium cutirubrum compared with those of its deoxy analogue, at the air/water interface

Quinn

Kates

Tocanne³

et al. 1989

Biochemical Journal

View full text Add to dashboard Cite

The relationship between area per molecule and surface pressure of monolayers of phosphatidylglycerol phosphate from extreme halophile Halobacterium cutrirubrum and its deoxy analogue, deoxyphosphatidylglycerol phosphate, spread at an air/water interface was examined. The effect of ionization of the primary and secondary acidic functions of the phosphate groups of the two lipids on surface characteristics of compression isotherms was determined by spreading monolayers on subphases with pH values ranging from below the apparent pKa of the primary ionization (pH 0) to greater than that of secondary ionization (pH 10.9). The limiting molecular area increases with decreasing pH below 2. Ionization of the primary phosphate functions of both phospholipids (with bulk pK1 values close to 4) is associated with a marked expansion of the films, as judged by values of limiting molecular area. Ionization of the secondary phosphate functions causes further expansion of the films, with the apparent pK2 of deoxyphosphatidylglycerol phosphate slightly less than that indicated for phosphatidylglycerol phosphate. Values of surface-compressibility modulus calculated from the surface characteristics of the phosphatidylglcerol phosphate monolayers showed that films spread on subphases with a pH of about the apparent pK1 of the primary phosphate functions were the least compressible. Increasing or decreasing subphase pH caused an increase in compressibility; this effect on compressibility was much less with monolayers of deoxyphosphatidylglycerol phosphate at high pH. The effect of inorganic counter-ions on monolayer characteristics of phosphatidylglycerol phosphate was examined by using subphases of NaCl concentrations varying from 0.01 to 1 M. The limiting molecular area was found to increase exponentially with respect to the subphase NaCl concentration.

show abstract

Section: Methodssupporting

confidence: 71%

Surface characteristics of phosphatidylglycerol phosphate from the extreme halophile Halobacterium cutirubrum compared with those of its deoxy analogue, at the air/water interface

Quinn

Kates

Tocanne³

et al. 1989

Biochemical Journal

View full text Add to dashboard Cite

show abstract

“…The role of phospholipids in cell membrane organization was studied through Langmuir Blodgett Technique (LBT) which can offer important models for investigation of the existing molecular forces at fluid interfaces. M. Tomoaia Cotisel and coworkers carry out thermodynamic and structural research on supramolecular structures of molecular and colloidal selfassociation, self-assembled and supramolecular structures of organic molecules, measure the surface potential of biomolecules, the transfer of LB structures on various solid supports, the interactions with drugs and offers essential information about biological process at fluid interfaces [36][37][38][39][40][41][42][43][44][45].…”

Section: Fig 3 Representative Scheme Of Phospholipid In Cell Membranementioning

confidence: 99%

Silymarin Based Complexes – a mini review

PALTINEAN¹,

Tomoaia²,

Riga³

et al. 2022

AnnalsARSciBio

View full text Add to dashboard Cite

Silymarin (SIL) is a component extracted from Silybum marianum herb and is studied in medicine due to its protective activities on certain organs (liver, kidney, heart, brain). The review discusses some methods that increase silymarin bioavailability such as development of complexes with cyclodextrins, phospholipids, liposome and nanostructured material (hydroxyapatite-HAP). The interactions between SIL and alpha-lipoic acid, metallic nanoparticles (gold nanoparticles-GNP, and silver nanoparticles – SNP), some carotenoids (β-carotene and lycopene) and curcumin were debated too. Some combined treatments (e.g. SIL + curcumin) highlighted anticancer activity against colon cancer cells (DLD-1, HCT116 and LoVo) and protective effect against chemicals toxicity.

show abstract

“…The SNPs self assembly is investigated in specialized literature by using Langmuir-Blodgett method [126]. This technique allow the preparation of ultrathin film of nanoparticles and their organization in lipid monolayer at air/water interface [127][128][129][130][131][132][133][134][135][136][137][138] or oil/water interface [125,126,139,140]. The manufacture of self-assembled structures at selected lateral pressures and the measurement of the surface potential of various biomolecules such as lipids, galactolipids, proteins, amino acids, fatty acids, carotenoids, is also possible and such research was conducted by a group of researchers in Romania [141][142][143][144][145][146][147][148][149][150][151].…”

Section: Characterization Of Silver Naoparticlesmentioning

confidence: 99%

Biomimetic and Antibacterial Composite for Orthopedic Implants

Balint¹,

Paltinean²,

FLOREA³

et al. 2022

AnnalsARSciBio

Self Cite

View full text Add to dashboard Cite

The present paper shows how the development of synthetic nanostructured biomaterials, such as multisubstituted hydroxyapatite (msHAP) with Mg2+, Zn2+ and Sr2+ ions is important and beneficial at the same time for the normal functioning of the body. Moreover, the paper discusses a broad topic of major importance in orthopedic and dental surgery, namely the incorporation of msHAP into the polymeric matrix of poly lactic acid (PLA). This composite is used in order to cover the surface of the titanium implant in order to obtain bone integration and heal bone fractures. The review also highlights the importance of improving silver nanoparticle (SNPs) coating in order to combat postoperative infections. Through such approaches, medicine has managed to evolve considerably, and the contributions brought by great personalities and young researchers in the field have increased its area of applicability.

show abstract

Monolayer properties of membrane lipids of the extreme halophile Halobacterium cutirubrum, at the air/water interface

Cited by 13 publications

References 14 publications

Surface characteristics of phosphatidylglycerol phosphate from the extreme halophile Halobacterium cutirubrum compared with those of its deoxy analogue, at the air/water interface

Surface characteristics of phosphatidylglycerol phosphate from the extreme halophile Halobacterium cutirubrum compared with those of its deoxy analogue, at the air/water interface

Silymarin Based Complexes – a mini review

Biomimetic and Antibacterial Composite for Orthopedic Implants

Contact Info

Product

Resources

About