Monoketone Curcuminoids: An Updated Review of Their Synthesis and Biological Activities
Tatiana M. Manzini Vieira,
Lívia Stenico Tanajura,
Vladimir Constantino Gomes Heleno
et al.
Abstract:Curcumin [1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadien-3,5-dione], a component of Curcuma longa L. rhizomes, displays various biological and pharmacological activities. However, it is poorly bioavailable and unstable in physiological pH, which has led more stable and effective curcumin analogs (e.g., monoketone curcuminoids, or MKCs) to be synthesized, and their biological activities to be described. In this review, we cover papers published between 2019 and 2023 on the antimicrobial, anticancer, antioxida… Show more
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