Monografias de Plantas Medicinais Brasileiras e Aclimatadas: Volume II

Gilbert, Benjamin Jacob; Alves, Lúcio Ferreira; Favoreto, Rita de Fátima

doi:10.7476/9786557081778

2022

DOI: 10.7476/9786557081778

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Monografias de Plantas Medicinais Brasileiras e Aclimatadas: Volume II

Benjamin Jacob Gilbert¹,

Lúcio Ferreira Alves²,

Rita de Fátima Favoreto³

Abstract: O presente volume contém monografias completas de 11 plantas medicinais amplamente empregadas no país, sendo apenas duas exóticas. Nenhuma dessas espécies possui monografia farmacopeica nas seis edições já publicadas da Farmacopeia Brasileira; portanto, é significativa a contribuição desta obra para o desenvolvimento de fitoterápicos, importantes para a Atenção Primária à Saúde, principalmente quando se considera que 82% da população brasileira utiliza produtos à base de plantas medicinais.

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Quantitative Chemical Composition, Anti-Oxidant Activity, and Inhibition of TNF Release by THP-1 Cells Induced by Extracts of Echinodorus macrophyllus and Echinodorus grandiflorus

Rocha

Gomes

et al. 2023

Antioxidants

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This study investigated the similarities between Echinodorus macrophyllus and Echinodorus grandiflorus, plant species that are traditionally used in Brazil to treat rheumatism and arthritis, whose anti-inflammatory effects are supported by scientific evidence. The contents of cis- and trans-aconitic acid, homoorientin, chicoric acid, swertisin, caffeoyl-feruloyl-tartaric acid, and di-feruloyl-tartaric acid were quantified by UPLC-DAD in various hydroethanolic extracts from the leaves, whereas their anti-oxidant activity and their effect on TNF release by LPS-stimulated THP-1 cells were assessed to evaluate potential anti-inflammatory effects. The 50% and 70% ethanol extracts showed higher concentrations of the analyzed markers in two commercial samples and a cultivated specimen of E. macrophyllus, as well as in a commercial lot of E. grandiflorus. However, distinguishing between the species based on marker concentrations was not feasible. The 50% and 70% ethanol extracts also exhibited higher biological activity, yet they did not allow differentiation between the species, indicating similar chemical composition and biological effects. Principal component analysis highlighted comparable chemical composition and biological activity among the commercial samples of E. macrophyllus, while successfully distinguishing the cultivated specimen from the commercial lots. In summary, no differences were observed between the two species in terms of the evaluated chemical markers and biological activities.

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Quantitative Chemical Composition, Anti-Oxidant Activity, and Inhibition of TNF Release by THP-1 Cells Induced by Extracts of Echinodorus macrophyllus and Echinodorus grandiflorus

Rocha

Gomes

et al. 2023

Antioxidants

View full text Add to dashboard Cite

show abstract

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Monografias de Plantas Medicinais Brasileiras e Aclimatadas: Volume II

Cited by 1 publication

References 329 publications

Quantitative Chemical Composition, Anti-Oxidant Activity, and Inhibition of TNF Release by THP-1 Cells Induced by Extracts of Echinodorus macrophyllus and Echinodorus grandiflorus

Quantitative Chemical Composition, Anti-Oxidant Activity, and Inhibition of TNF Release by THP-1 Cells Induced by Extracts of Echinodorus macrophyllus and Echinodorus grandiflorus

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