Monogamy and polygamy relations characterize the distributions of entanglement in multipartite systems. We provide a characterization of multiqubit entanglement constraints in terms of unified-$(q,s)$ entropy. A class of tighter monogamy inequalities of multiqubit entanglement based on the $\alpha$-th power of unified-$(q,s)$ entanglement for $\alpha\geq 1$ and a class of polygamy inequalities in terms of the $\beta$-th power of unified-$(q,s)$ entanglement of assistance are established in this paper. Our results present a general class of the monogamy and polygamy relations for bipartite entanglement measures based on unified-$(q,s)$ entropy, which are tighter than the existing ones. What's more, some usual monogamy and polygamy relations, such as monogamy and polygamy relations based on entanglement of formation, Renyi-$q$ entanglement of assistance and Tsallis-$q$ entanglement of assistance, can be obtained from these results by choosing appropriate parameters $(q,s)$ in unified-$(q,s)$ entropy entanglement. Typical examples are also presented for illustration.