Monodisperse and fluorescent poly(styrene-co-methacrylic acid-co-2-naphthyl methacrylate)/Fe3O4 composite particles

Govindaiah, Patakamuri; Jung, Yeon Jae; Lee, Jung Min; Park, Tae Joon; Ryu, Du Yeol; Kim, Jung Hyun; Cheong, In Woo

doi:10.1016/j.jcis.2009.11.059

Cited by 15 publications

(11 citation statements)

References 45 publications

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“…TGA curve is illustrated in Figure 7. It is expected that as theaminated-Fe 3 O 4 composite particles are heated from ambient temperature to 600˚C, the organic part of the Considering the larger average size of the composite particles, the percentage of magnetic iron oxide is pretty high to modify the particles surface [64]. Figure 8 shows the adsorption behaviors of TR on the PS seed and aminated-Fe 3 O 4 composite particles.…”

Section: Adsorption Of Trypsin (Tr) On Ps Seed and Aminated-fe 3 O 4 mentioning

confidence: 99%

Preparation of Micron-Sized Di-Functional Magnetic Composite Polymer Particles

Ahmad¹,

Tofaz²,

Oli³

et al. 2010

MSA

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In this investigation micron-sized monodisperse magnetic composite polymer particles with amino and amide functional groups were prepared considering their applications in biotechnology. First, polystyrene/poly (acrylic acid-acrylam- ide-N-N-methylene-bis-acrylamide) [PS/P(AA-AAm-MBAAm)] composite polymer particles were prepared by seeded copolymerization. The carboxyl groups present on or near the particles surface were modified by amine-nucleophile, ethylene diamine (EDA), through pre-activation with dicyclohexyl carbodiimide as coupling agent. The aminated particles were then magnetically modified and named as aminated-Fe3O4 composite particles. Formation of such magnetic composite particles was confirmed by scanning electron micrographs, FTIR-spectra and magnetic susceptibility measurement. The produced composite particles were paramagnetic. To see the relative hydrophilic character of the particles surface the adsorption behavior of trypsin (TR) as biomolecule was studied on PS particles and aminated-Fe3O4 composite particles. The magnitude of adsorbed TR on PS particles was higher than that on aminated-Fe3O4 composite particles

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Section: Adsorption Of Trypsin (Tr) On Ps Seed and Aminated-fe 3 O 4 mentioning

confidence: 99%

Preparation of Micron-Sized Di-Functional Magnetic Composite Polymer Particles

Ahmad¹,

Tofaz²,

Oli³

et al. 2010

MSA

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show abstract

“…We have examined the effect of fluorescent magnetic submicronic polymer nanoparticles (FMSPnanoparticles) on human colorectal carcinoma cell line (HCT-116). There are several reports of use of fluorescent magnetic nanoparticles in many biological and diagnostic applications [20][21][22][23][24][25][26], but not much known about their anti-cancer properties especially in the colorectal cancers. In the present study, we have tested for the first time, the effect of FMSP-nanoparticles on HCT-116.…”

Section: Introductionmentioning

confidence: 99%

Fluorescent magnetic submicronic polymer (FMSP) nanoparticles induce cell death in human colorectal carcinoma cells

Khan

Akhtar

Almohazey

et al. 2018

Artificial Cells, Nanomedicine, and Biotechnology

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Nanoparticles have many advantages such as high biocompatibility, bioavailability and effective therapeutic capabilities. The aim of the present study is to examine whether fluorescent magnetic submicronic polymer nanoparticles (FMSP-nanoparticles) have any impact on human colorectal cancer cells. In the present study, we have tested FMSP-nanoparticles with an average size of 100-200 nm on human colorectal carcinoma cells (HCT-116) to check their cytotoxic and anti-cancer capabilities. The effects of FMSP-nanoparticles on cancer cells were observed after 6 h, 24 h and 48 h intervals. The response of FMSP-nanoparticles-treated cells was evaluated by Trypan Blue, 4lue-diamidino-2-phenylindole (DAPI) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays. Our MTT analysis results revealed that FMSP-nanoparticles produced dose-dependent effects on cancer cells, FMSP-nanoparticles with dose of 1.25 µg/mL did not decrease cell survivability, whereas dosages of 12.5 µg/mL and 50 µg/mL respectively showed 23.59% and 59.47% decrease in the cancer cell survivability. In conclusion, our results demonstrate FMSP-nanoparticles have a potential anti-cancer capability and hold a great promise for colon cancer treatments.

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“…[13,[37][38][39][40][41] Notably, carbazole-based polymer microspheres have emergeda s promising matrices for photoelectric devicesa nd sensors.S everal polymerization approaches, including emulsion, dispersion, and suspension polymerization are availablef or the prepara-tion of polymer microspheres. [35,42] However, to the best of our knowledge, fluorescent porousc arbazole-based polymerm icrospheres prepared by soap-free emulsion polymerization of carbazole monomer (N-vinylcarbazole, NVCz)h as not been reported until now. [35,42] However, to the best of our knowledge, fluorescent porousc arbazole-based polymerm icrospheres prepared by soap-free emulsion polymerization of carbazole monomer (N-vinylcarbazole, NVCz)h as not been reported until now.…”

Section: Introductionmentioning

confidence: 99%

Fluorescent Porous Carbazole‐Decorated Copolymer Monodisperse Microspheres: Facile synthesis, Selective and Recyclable Detection of Iron (III) in Aqueous Medium

Luo

Lun

et al. 2018

Chemistry A European J

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We demonstrate an environmentally friendly one-step soap-free emulsion polymerization strategy to develop fluorescent carbazole-based copolymer monodisperse microspheres for highly sensitive and selective detection of Fe . The copolymer microspheres feature a stable spherical morphology with a narrow size distribution through regulating N-vinylcarbazole (NVCz) content (1.25-10.0 wt.%). Notably, the as-made microspheres exhibit a strong luminescence, tunable emission intensity and specific surface areas. Interestingly, the fluorescence of the copolymer microspheres can be selectively quenched by trace amounts of Fe due to the oxidation of carbazole, and the quenching fluorescence can be facilely recovered by reduction with NaBH . Its excellent sensing performance is shown in terms of high sensitivity (low limit of detection, 1.3 μm), excellent selectivity, and rapid response rate, due to the porous nature of the copolymer microspheres. These results illustrate the copolymer microspheres obtained by simple preparative procedure without using expensive or toxic raw materials would serve as a high performance sensor for highly selective and recyclable detection of Fe in aqueous medium.

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Monodisperse and fluorescent poly(styrene-co-methacrylic acid-co-2-naphthyl methacrylate)/Fe3O4 composite particles

Cited by 15 publications

References 45 publications

Preparation of Micron-Sized Di-Functional Magnetic Composite Polymer Particles

Preparation of Micron-Sized Di-Functional Magnetic Composite Polymer Particles

Fluorescent magnetic submicronic polymer (FMSP) nanoparticles induce cell death in human colorectal carcinoma cells

Fluorescent Porous Carbazole‐Decorated Copolymer Monodisperse Microspheres: Facile synthesis, Selective and Recyclable Detection of Iron (III) in Aqueous Medium

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