Monoclonal gammopathies of renal significance

Gnanasampanthan, Sahana; Kousios, Andreas

doi:10.7861/clinmed.2023-rm3

Cited by 3 publications

(2 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…MGRS is a disorder caused by monoclonal immunoglobulins secreted by clones of nonmalignant plasma cells or B cells (13). PGNMID is a specific type of MGRS (14).…”

Section: Discussionmentioning

confidence: 99%

IgM kappa proliferative glomerulonephritis with monoclonal immunoglobulin deposition complicated with nocardiosis dermatitis: a case report and review of literature

Chen,

Wang,

et al. 2024

Front. Med.

View full text Add to dashboard Cite

RationaleMonoclonal gammopathy of renal significance (MGRS) represents a group of disorders caused by monoclonal immunoglobulin (M protein) secreted by B cells or plasma cells. Proliferative glomerulonephritis with monoclonal immunoglobulin deposition (PGNMID) is a glomerular disease and a form of MGRS. Here, we presented a rare case of a patient with IgM kappa PGNMID complicated with nocardiosis dermatitis.Patient concerns and diagnosesA 56-year-old man was admitted to the hospital because of cutaneous purpura and proteinuria. His initial pathological diagnosis indicated membranous proliferative glomerulonephritis, IgM(++), and subacute interstitial nephritis. Based on further examination, he was finally diagnosed to have IgM kappa PGNMID and subacute interstitial nephritis. After the initial diagnosis, the patient received hormonal therapy. During the treatment, nocardiosis dermatitis emerged as a complication, and the hormonal therapy was gradually reduced. The patient refused further treatment with rituximab, and his health is currently stable.OutcomesIgM kappa PGNMID complicated with nocardiosis dermatitis is an extremely rare occurrence. Laboratory examination and pathological analysis are required to confirm the diagnosis of this disorder. Timely and accurate diagnosis is essential for the appropriate treatment of PGNMID.

show abstract

“…MGRS is a disorder caused by monoclonal immunoglobulins secreted by clones of nonmalignant plasma cells or B cells (13). PGNMID is a specific type of MGRS (14).…”

Section: Discussionmentioning

confidence: 99%

IgM kappa proliferative glomerulonephritis with monoclonal immunoglobulin deposition complicated with nocardiosis dermatitis: a case report and review of literature

Chen,

Wang,

et al. 2024

Front. Med.

View full text Add to dashboard Cite

show abstract

“…This month's CME topic is on renal medicine, presenting the customary high quality up-to-date reviews on a range of topics. [8][9][10][11] Allied to opinion pieces on ChatGPT 12 and the usual range of clinical cases and images, this edition of the journal reflects the breadth of clinical content that is the hallmark of ClinMed. ■…”

mentioning

confidence: 99%