Abstract:The pathway a growing axon follows is determined by a number of cues, including differential adhesion to surface molecules on axons and the matrix of the fascicles along which they grow. We have characterized the differential expression of an extracellular antigen and the effects of a monoclonal antibody against this molecule on the development of the grasshopper central nervous system (CNS). The 5C1 monoclonal antibody was generated against ganglion chains of grasshopper embryos; it labels cell bodies of newl… Show more
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