Monocentric prospective study for assessing the efficacy and tolerability
                        of a cosmeceutical formulation in patients with melasma

Ayres, Eloísa Leis; Costa, Adilson; Jorge, A; Júnior, José Euzébio Gonçalves; Szrajbman, Miriam; Sant’Anna, Beatriz

doi:10.5935/scd1984-8773.201683832

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Digital image analysis of photographs: Digital image photographs were taken every session used to determine the degree of improvement of the melasma lesion. Measurement of the efficacy of the treatment: Efficacy of the treatment=(mMASI score before-mMASI score after)/mMASI score before x 100 [7] .…”

Section: Therapeutic Regimenmentioning

confidence: 99%

Comparative Study between Topical Flutamide Alone or Combined with Carboxytherapy in Treatment of Patients with Melasma

El-Maghraby

El-Adawy

2019

The Medical Journal of Cairo University

View full text Add to dashboard Cite

Background: Melasma is one of the most common causes of facial hyperpigmentation which causes cosmetic disfigurement and leads to psychological proplems, although various treatments are available for melasma, it remains a difficult condition to treat. Aim of Study : To evaluate and compare the efficacy of topical flutamide 1% alone and in-combination with Carboxytherapy in treatment of patients with melasma. Patients and Methods: The study included 30 female patients with different types and patterns of melasma. They were divided into two groups, each group included 15 patients: Group A, patients were treated with 1 % flutamide topical gel on the face and group B, patients were treated with 1 % flutamide topical gel on the face and carboxytherapy injection was done in both sides of the face every four weeks for three sessions. Results: Both groups showed highly significant decrease in mMASI score after the treatment in which group B showed better results with (p-value=0.048*) than group A with (p-value=0. 007*). Conclusion: As new treatment for melasma topical flutamide was effective and safe therapeutic modalities. Carboxytherapy could be effective and safe new treatment modality for melasma as adjuvant treatment with topical flutamide.

show abstract

Section: Therapeutic Regimenmentioning

confidence: 99%