monoamine oxidase inhibitors revisited

Wells, Douglas G.; Bjorksten, Andrew R.

doi:10.1007/bf03010890

Cited by 54 publications

(16 citation statements)

References 66 publications

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“…80 Classic MAOI, phenelzine and tranylcypromine, irreversibly inhibit MAO for two to three weeks until a new enzyme is synthesized. 80 Moclobemide, a reversible inhibitor of MAO-A (RIMA) causes enzyme inhibition for less than 24 hr. 81,82 Selegiline, an antiParkinsonian agent, is a short-acting, reversible MAO-B inhibitor at its usual dose.…”

Section: Is Postoperative Fever An Indication For Hospital Admission?mentioning

confidence: 99%

“…83 What is the evidence linking MAOI to serotonergic crises? Serotonergic reactions to meperidine have been described for all MAOI, 80,84,85 including moclobemide 81,82 and selegiline. 83 Meperidine blocks neuronal serotonin reuptake, resulting in serotonergic overactivity, agitation, hyper/hypotension, convulsions, hyperthermia, and coma.…”

Section: Is Postoperative Fever An Indication For Hospital Admission?mentioning

confidence: 99%

“…83 Meperidine blocks neuronal serotonin reuptake, resulting in serotonergic overactivity, agitation, hyper/hypotension, convulsions, hyperthermia, and coma. 82 However, serotonin concentration must reach a critical level, as evidenced by one patient who reacted to meperidine only after increasing her phenelzine dose 80 and by a randomized, controlled trial, in which 15 patients on MAOI given meperidine and morphine all responded normally. 85 Cocaine also reduces serotonin inactivation and blocks monoamine reuptake.…”

Section: Is Postoperative Fever An Indication For Hospital Admission?mentioning

confidence: 99%

“…85 Cocaine also reduces serotonin inactivation and blocks monoamine reuptake. 80,86 A delayed excitatory reaction occurred in a patient on phenelzine 70 min after topical laryngeal cocaine. 86 Serotonergic crises may follow the administration of meperidine or cocaine (grade C).…”

Section: Is Postoperative Fever An Indication For Hospital Admission?mentioning

confidence: 99%

“…80 A patient on selegiline developed hypertension and supraventricular tachycardia after receiving ephedrine 87 whereas a patient who omitted one dose of moclobemide responded normally to both phenylephrine and ephedrine. 81 Indirect-acting catecholamines should be avoided (grade C).…”

Section: Are Maoi Associated With Atypical Responses To All Catecholamentioning

confidence: 99%

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Patient selection in ambulatory anesthesia — An evidence-based review: part II

et al. 2004

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P Pu ur rp po os se e: : This is the second of two reviews evaluating the management of patients with selected medical conditions undergoing ambulatory anesthesia and surgery. Conditions highlighted in this review include: diabetes mellitus; morbid obesity; the ex-premature infant; the child with an upper respiratory infection; malignant hyperthermia; and the use of monoamine oxidase inhibitors.S So ou ur rc ce e: : Medline search strategies and the framework for the evaluation of clinical evidence are presented in Part I. P Pr ri in nc ci ip pa al l f fi in nd di in ng gs s: : Diabetes mellitus has not been linked with adverse events following ambulatory surgery. The morbidly obese patient is at an increased risk for minor respiratory complications in the perioperative period but these events do not increase unanticipated admissions. The ex-premature infant may be considered for ambulatory surgery if post-conceptual age is > 60 weeks and hematocrit is > 30%. The child with a recent upper respiratory tract infection is at an increased risk for perioperative respiratory complications, particularly if endotracheal intubation is required. Patients with malignant hyperthermia may undergo outpatient surgery but require four hours of postoperative temperature monitoring. Sporadic cases of drug interactions have been reported when meperidine and indirectacting catecholamines are administered in the presence of monamine oxidase inhibitors. Ambulatory anesthesia and surgery is safe if these combinations of drugs are avoided.C Co on nc cl lu us si io on n: : Ambulatory anesthesia can be performed in, and is being offered to, a variety of patients with significant coexistent disease. In many cases there is little evidence documenting the outcomes expected in such patients. Prospective observational and interventional trials are required to better define perioperative management. Objectif : C'est la seconde revue qui évalue la prise en charge de patients, dont les pathologies médicales ont été ciblées, qui doivent subir une anesthésie en chirurgie ambulatoire. Les situations choisies comprennent : le diabète, l'obésité morbide, l'enfant né prématurément, l'enfant atteint d'infection des voies respiratoires supérieures, l'hyperthermie maligne et l'usage d'inhibiteurs de la monoamine-oxydase. Source : Les stratégies de recherche dans Medline et le cadre de l'é-valuation de la preuve clinique sont présentés dans la partie I. Constatations principales : Le diabète n'a pas été relié à des événements indésirables à la suite d'une opération ambulatoire. Le patient très obèse est plus à risque de complications respiratoires péri-opératoires mineures, ce qui n'augmente pas les admissions hospitalières imprévues. L'enfant prématuré est admis en chirurgie ambulatoire si l'âge post-conception est > 60 semaines et si l'hématocrite est > 30 %. L'enfant qui a une infection récente des voies respiratoires supérieures

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