Mono-osteitic Paget's disease as a clinical entity. Roentgenologic observations in nine cases. By J. A. Groh, 1943

Abstract

ANNIVERSARY REPRINT 235This paper is reprinted verbatim from AJR 1943:50:230-243.

Clinical and radiographic improvement of bone of the second lumbar vertebra in paget's disease following therapy with etidronate disodium: A case report

“…While most patients with Paget's disease of bone do not develop the extensive bony deformities and malignant neoplasms seen in the initial patient Paget described (l), the natural history of the untreated disease is one of slow progression or quiescence rather than spontaneous regression. Groh (7) in 1943 reported a series of 11 cases of Paget's disease. Nine patients had monostotic disease (involving 6 different vertebral bodies), 2 had polyostotic disease, and no patient demonstrated any radiographic im-B provement.…”