Mono, bi- and trinuclear metal complexes derived from new benzene-1,4-bis(3-pyridin-2-ylurea) ligand. Spectral, magnetic, thermal and 3D molecular modeling studies

El-ghamry, Mosad A.; Saleh, Akila A.; Khalil, Saied M. E.; Mohammed, Amira A.

doi:10.1016/j.saa.2013.03.016

Cited by 24 publications

(16 citation statements)

References 52 publications

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“…Metalnitrogen and M-Oxygen bands were further confirmed as coordination sites by the presence of the stretching vibrations of υ(M-N) and υ(M-O) around 418 cm -1 -468.70 cm -1 and 511.14 cm -1 -545.21 cm -1 respectively. Furthermore, the bands of coordinated water observed at the range of 842 cm -1 -869 cm -1 support the proof that there is the presence of water in the lattice of the complexes (Dilip, et al, (2012), El-Ghamry et al, (2013) and Shebl et al, 2010).…”

Section: Resultssupporting

confidence: 70%

Synthesis, characterization and antimicrobial activity of mixed transition metal complexes of salicylic acid with 1, 10-phenanthroline

Lawal¹,

Shodeinde²,

Amolegbe³

et al. 2017

Journal of Applied Sciences and Environmental Management

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ABSTRACT:A new series of Mn(II), Fe(II), Co(II), Cu(II) and Zn(II) mixed ligands-metal complexes derived from salicylic acid (SA) and 1,10-phenanthroline (PHEN) have been synthesized and characterized by spectroscopic studies. The coordination of the two ligands towards central metal ions has been proposed in the light of elemental analysis, IR, UV-vis spectroscopic studies. The results of the physical and spectroscopic data confirmed that the ligands are chelating agents. In 1, 10-phenanthroline, coordination occurred through the two pyridinic nitrogen groups, while in the salicylic acid coordination occurred through the oxygen of the hydroxyl and the carboxylic groups. All the complexes synthesized were of octahedral geometry.Antimicrobial activity of the mixed ligands metal complexes and the free ligands were carried out against the bacterial Escherichia coli, staphylococcus aureus, klebsiella pneumonia, pseudomonas aeruginosa and the fungi candida spp. The mixed ligands metal complexes showed higher activities when compared to the free ligands of salicylic acid but were less active than the free 1,10-phenanthroline ligand. The complexes of Cu (II) showed the highest antimicrobial activity while the Fe(II ) complex showed the least activity against the bacterial and fungi organisms. © JASEM https://dx.doi.org/10.4314/jasem.v21i3.18

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Section: Resultssupporting

confidence: 70%

Synthesis, characterization and antimicrobial activity of mixed transition metal complexes of salicylic acid with 1, 10-phenanthroline

Lawal¹,

Shodeinde²,

Amolegbe³

et al. 2017

Journal of Applied Sciences and Environmental Management

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“…[29] The low conductance values observed for some complexes may be due to partial displacement of coordinated NO 3 − ions by DMF solvent molecules. [30]…”

Section: Characterization Of the Metal Complexesmentioning

confidence: 99%

Synthesis and structural characterization of nano‐sized metal complexes of 3‐(1‐methyl‐4‐hydroxy‐2‐oxo‐1,2‐dihydroquinolin‐3‐yl)‐2‐nitro‐3‐oxopropanoic acid. XRD, thermal, 3D modeling, and antitumor activity studies

El-ghamry

El‐Shafiy

2021

Applied Organom Chemis

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New Co(II), Ni(II), Cu(II), Zn(II), and Fe(III) complexes of the ligand 3-(1-methyl-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-2-nitro-3-oxopropanoic acid (H 3 L) were synthesized and characterized by various analytical and spectroscopic techniques. The obtained data confirmed the formation of 1:1 (M:L) stoichiometry for Fe(III), Co(II) complexes and 2:1 (M:L) stoichiometry for Ni(II), Cu(II), Zn(II) complexes, and the ligand, H 3 L, acts as mono-, bi-, tribasic bis-, tris-and tetradentate towards the metal ions via the oxygen of quinolinonate, the enolic/ketonic of β-ketoacid, and carboxylate besides of the nitro groups. All complexes showed tetrahedral geometry, except Fe(III) complex which exhibited an octahedral geometry. The X-ray diffractograms of the ligand, H 3 L, and its metal complexes revealed a series of sharp and intense diffraction peaks which indicate their crystalline characteristic with the particle size in the nano-scale range. Geometrical optimizations of the ligand, H 3 L, and its metal complexes were performed at the B3LYP/6-311G(d, p) level using density functional theory (DFT) implemented in the Gaussian 09 program.The data obtained were correlated with the experimental results and suggested that the Zn(II) complex may exhibit extremely bio-efficiency than other compounds. The antimicrobial screening results showed enhancement in the efficiency of the free ligand, H 3 L, on coordination with the metal ions. The antitumor activity was evaluated in vitro against Hepatocellular carcinoma cell line (HepG-2 cells). The ligand, H 3 L, and its Zn(II) complex showed strong antitumor activities, especially nano-sized Zn(II) complex that exhibited IC 50 value (2.90 μg/ml) smaller than the well-known standard antitumor drug cisplatin (IC 50~3 .27 μg/ml), prominent it as an antitumor agent towards HepG-2 cells.

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“…The IR spectrum of the Sud III binary complex showed bands at 820 and 897 cm −1 characteristic of coordinated water molecules and the ν(MO) stretching vibration bands of coordinated water attachment to metal ions were found at 508 cm −1 …”

Section: Resultsmentioning

confidence: 99%

Construction and characterization of nano iron complex ionophore for electrochemical determination of Fe(III) in pure and various real water samples

Ali

Mahmoud

2019

Applied Organom Chemis

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Electrochemical methods represent an important class of widely used techniques for the detection of metal ions. The unique chemical and physical properties of nanoparticles make them extremely suitable for designing new and improved sensing devices, especially electrochemical sensors and biosensors. This study focused on the synthesis of a nano-Fe(III)-Sud complex and its characterization using various spectroscopic and analytical tools, optimized using the density functional theory method, screened for antibacterial activity and evaluated for possible binding to DNA using molecular docking study. Proceeding from the collected information, nano-Fe(III)-Sud was used further for constructing carbon paste and screen-printed ion-selective electrodes. The proposed sensors were successfully applied for the determination of Fe(III) ions in various real and environmental water samples. Some texture analyses of the electrode surface were conducted using atomic force microscopy. At optimum values of various conditions, the proposed electrodes responded towards Fe(III) ions linearly in the range 2.5 × 10 −9 -1 × 10 −2 and 1.0 × 10 −8 -1 × 10 −2 M with slope of 19.73 ± 0.82 and 18.57 ± 0.32 mV decade −1 of Fe(III) ion concentration and detection limit of 2.5 × 10 −9 and 1.0 × 10 −8 M for Fe(III)-Sud-SPE (electrode I) and Fe(III)-Sud-CPE (electrode II), respectively. The electrode response is independent of pH in the range 2.0-7.0 and 2.5-7.0, with a fast response time (4 and 7 s) at 25°C for electrode I and electrode II, respectively.Moreover, the electrodes also showed high selectivity and long lifetime (more than 6 and 3 months for electrode I and electrode II, respectively). The electrodes showed good selectivity for Fe(III) ions among a wide variety of metal ions. The results obtained compared well with those obtained using atomic absorption spectrometry.

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Mono, bi- and trinuclear metal complexes derived from new benzene-1,4-bis(3-pyridin-2-ylurea) ligand. Spectral, magnetic, thermal and 3D molecular modeling studies

Cited by 24 publications

References 52 publications

Synthesis, characterization and antimicrobial activity of mixed transition metal complexes of salicylic acid with 1, 10-phenanthroline

Synthesis, characterization and antimicrobial activity of mixed transition metal complexes of salicylic acid with 1, 10-phenanthroline

Synthesis and structural characterization of nano‐sized metal complexes of 3‐(1‐methyl‐4‐hydroxy‐2‐oxo‐1,2‐dihydroquinolin‐3‐yl)‐2‐nitro‐3‐oxopropanoic acid. XRD, thermal, 3D modeling, and antitumor activity studies

Construction and characterization of nano iron complex ionophore for electrochemical determination of Fe(III) in pure and various real water samples

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