Mono and Dinuclear Cu(II) Carboxylate Complexes with Pyridine and 1‐methylimidazole as Co–Ligands: Synthesis, Structure, Antibacterial Activity and Catalytic Nitroaldol Reactions

Abstract

A new series of Cu(II) carboxylate complexes [Cu2(RCOO)4(Py)2] (1 & 2) and [Cu(RCOO)2(MIm)2] (3 & 4) {RCOO=p–FBA (p‐fluorobenzoic acid), BA (benzoic acid), Py (Pyridine), MIm (1–methylimidazole)} have been synthesized. The composition of complexes (1–4) has been established by spectral (FTIR, UV/Vis & EPR) methods and elemental analysis. Molecular structures of copper(II) carboxylate complexes [Cu2(p–FBA)4(Py)2] (1) and [Cu(p–FBA)2(MIm)2] (3) were established by X–ray diffraction. These copper(II) carboxylate complexes 1–4 exhibit a very good catalytic activity towards nitroaldol (Henry) reaction of various aldehydes with nitromethane. The ligands and copper(II) complexes were also screened for their antibacterial activity against microorganisms Staphylococcus aureus and Escherichia coli.

Synthesis, characterization, antioxidant, antileishmanial, anticancer, DNA and theoretical SARS-CoV-2 interaction studies of copper(II) carboxylate complexes

“…Carboxylic acids ( HL 1 and HL 2 ) and copper complexes ( 1 and 2 ) were assessed in vitro for their DPPH free radical scavenging potentials following a reported procedure [45] . Different concentrations (15, 30, 60, 120 and 240 μ M) of the test compounds were mixed with 1000 μ L ethanolic solution of DPPH (255 μ M).…”

Synthesis and Characterization of Slow-Release Chitosan Oligosaccharide Pyridine Schiff Base Copper Complexes with Antifungal Activity

“…A comparison of the FT-IR spectra of CPSx and CPSx-Cu complexes shows that the peaks of the bending vibrations of C–H in pyridine shift to higher frequencies in the FT-IR spectra of CPSx-Cu complexes (CPS1-Cu = 945 cm –1 , 899 cm –1 , and 777 cm –1 ; CPS2-Cu = 948 cm –1 , 899 cm –1 , and 780 cm –1 ; CPS3-Cu = 945 cm –1 , 898 cm –1 , and 783 cm –1 ), whereas the peaks of the absorption bands of NC–H remain unchanged. This implies that the nitrogen atom in pyridine, and not the nitrogen atom of imine, forms a coordination bond with the copper ion …”

Self-assembled iRGD-R7-LAHP-M nanoparticle induced sufficient singlet oxygen and enhanced tumor penetration immunological therapy

“…The shoulder peak at 340 nm in the ultraviolet region belongs to Fe(III) in LAHP-Fe(III) complexes and the broad bands at 800-600 nm (d → d transition) in the visible region for Cu(II) in the LAHP-Cu(II) complex. 31,32,33 To reveal the chemical composition profiles of LAHP-M complexes, infrared spectroscopy (IR) was used, as shown in Fig. 2E.…”