“…Histaminase activity is reported to be decreased in preeclamptic toxemia, after adrenalectomy, and in subjects with low copper intake Very few studies have been done on plasma and/or tissue histaminase in various malignancies. Increased histaminase activity has been observed in bronchial carcinoma, endometrial carcinoma, small-cell carcinoma of the lung, medullary carcinoma of the thyroid gland, and ovarian carcinoma [14][15][16][17][18][19][20][21][22][23][24], but Starr et a1 [25] observed the absence of histaminase in all the tumors except lymph node metastasis of gastric adenocarcinoma.…”