Monkeypox virus preparation in Pakistan-Next viral zoonotic disease outbreak after COVID-19?

Abstract

Monkeypox is a viral disease that often affects central and western African rainforests. But the illness has recently arisen in the World in imported African wild rats. Monkeypox exhibits symptoms that are remarkably similar to other types of smallpox, including flu-like symptoms, malaise, headache, back pain, fever, and the distinctive rash. Considering this therapeutic range, performing a differential diagnosis to exclude smallpox is critical. Monkeypox has no recognized treatment, but the smallpox vaccination can prevent the infection. Reducing contact with sick patients or animals and avoiding respiratory exposure to infected patients is vital for proper protection. ‎

The monkeypox diagnosis, treatments and prevention: A review

“…This review will examine the present state of knowledge on human MPX, focusing on epidemiology features, diagnosis, prevention, clinical aspects, and therapy. Furthermore, the increasing number of MPX cases in non-endemic countries has made it a public health threat for other countries like Pakistan ( Khattak et al., 2022b ). The situation requires disease surveillance at a country level, and timely detection and notification of suspected cases are essential for effective preventive measures.…”

Mechanistic inhibition of Monkeypox and Marburg virus infection by O-rhamnosides and Kaempferol-o-rhamnosides derivatives: a new-fangled computational approach

“…This virus is the most commonly found in Western and Central Africa ( Chakraborty C. et al., 2022 ; Velavan and Meyer, 2022 ). The clinically significant illness produced by Mpox is comparable to those seen in smallpox but is not as devastating ( Harapan et al., 2020 ; Khattak et al., 2022 ). This pathogenic virus was first reported in 1970 in an infant who had previously been affected by smallpox ( Ladnyj et al., 1972 ).…”