Monkeypox infection with localized genital lesions in women

Portela-Dias, Joana; Sereno, Sara; Falcão-Reis, Inês; Rasteiro, Cátia

doi:10.1016/j.ajog.2022.08.046

Cited by 11 publications

(16 citation statements)

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“…122 And genital rashes were observed in many cases, which was also recently proven in another studies. [264][265][266][267][268][269][270] Other recent reports describe similar clinical characteristics. 180,271,272 Patel and colleagues 272 demonstrated that all 197 monkeypox infection cases developed mucocutaneous lesions, typically in the genitals (111 of 197 patients) or the perianal areas, causing rectal pain and penile edema.…”

Section: Clinical Characteristicssupporting

confidence: 60%

Monkeypox: epidemiology, pathogenesis, treatment and prevention

Huang

Wang

2022

Sig Transduct Target Ther

141

120

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Monkeypox is a zoonotic disease that was once endemic in west and central Africa caused by monkeypox virus. However, cases recently have been confirmed in many nonendemic countries outside of Africa. WHO declared the ongoing monkeypox outbreak to be a public health emergency of international concern on July 23, 2022, in the context of the COVID-19 pandemic. The rapidly increasing number of confirmed cases could pose a threat to the international community. Here, we review the epidemiology of monkeypox, monkeypox virus reservoirs, novel transmission patterns, mutations and mechanisms of viral infection, clinical characteristics, laboratory diagnosis and treatment measures. In addition, strategies for the prevention, such as vaccination of smallpox vaccine, is also included. Current epidemiological data indicate that high frequency of human-to-human transmission could lead to further outbreaks, especially among men who have sex with men. The development of antiviral drugs and vaccines against monkeypox virus is urgently needed, despite some therapeutic effects of currently used drugs in the clinic. We provide useful information to improve the understanding of monkeypox virus and give guidance for the government and relative agency to prevent and control the further spread of monkeypox virus.

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Section: Clinical Characteristicssupporting

confidence: 60%

Monkeypox: epidemiology, pathogenesis, treatment and prevention

Huang

Wang

2022

Sig Transduct Target Ther

141

120

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“…Localized vulval lesions have been reported in a woman with a history of unprotected sexual activity with a new partner 26 . Isolated infralabial vesicopustule mimicking nodulocystic acne has been observed.…”

Section: Clinical Featuresmentioning

confidence: 94%

“…Atypical manifestations observed during the current outbreak Localized vulval lesions have been reported in a woman with a history of unprotected sexual activity with a new partner. 26 Isolated infralabial vesicopustule mimicking nodulocystic acne has been observed. Monkeypox whitlow, chancriform perianal ulcers, tonsillar ulcers, and proctitis are other manifestations which are less likely to be recognized as monkeypox by the physicians.…”

Section: Clinical Featuresmentioning

confidence: 98%

“…Umbilicated vesicopustules or pseudopustules may be confused with translucent umbilicated papules of genital molluscum contagiosum, particularly in patients presenting with lesions confined to the genitalia. 26 Lastly, presentation of monkeypox as a solitary genital ulcer has been well documented in the literature and needs differentiation from other sexually transmitted infections that present as genital ulcers, such as syphilis and chancroid. 28 Co-infection of monkeypox with several STIs has been observed, and evidence of one or more STIs should not exclude the diagnosis of monkeypox infection.…”

Section: Differential Diagnosismentioning

confidence: 99%

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Monkeypox: a new global health emergency with predominant dermatological manifestations

et al. 2022

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“…The classic MPXV cases were characterized by a generalized rash. In contrast, most of the cases in the current outbreak have localized lesions in anogenital and genitourinary areas [ 36 , 37 ]. Since many recent MPXV-infected cutaneous images have been reported, the updated dataset may have added value to the above MPXV 2022 image dataset.…”

Section: Monkeypox Diagnosis Approachesmentioning

confidence: 99%

Current and Perspective Sensing Methods for Monkeypox Virus

et al. 2022

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The outbreak of the monkeypox virus (MPXV) in non-endemic countries is an emerging global health threat and may have an economic impact if proactive actions are not taken. As shown by the COVID-19 pandemic, rapid, accurate, and cost-effective virus detection techniques play a pivotal role in disease diagnosis and control. Considering the sudden multicountry MPXV outbreak, a critical evaluation of the MPXV detection approaches would be a timely addition to the endeavors in progress for MPXV control and prevention. Herein, we evaluate the current MPXV detection methods, discuss their pros and cons, and provide recommended solutions to the problems. We review the traditional and emerging nucleic acid detection approaches, immunodiagnostics, whole-particle detection, and imaging-based MPXV detection techniques. The insights provided in this article will help researchers to develop novel techniques for the diagnosis of MPXV.

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Monkeypox infection with localized genital lesions in women

Cited by 11 publications

References 0 publications

Monkeypox: epidemiology, pathogenesis, treatment and prevention

Monkeypox: epidemiology, pathogenesis, treatment and prevention

Monkeypox: a new global health emergency with predominant dermatological manifestations

Current and Perspective Sensing Methods for Monkeypox Virus

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