Monkeypox in children: Update on the current outbreak and need for better reporting

Khalil, Asma; Samara, Athina; O’Brien, Pat; Ladhani, Shamez

doi:10.1016/j.lanepe.2022.100521

Cited by 7 publications

(4 citation statements)

References 2 publications

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“…One possible explanation is that children and adolescents may be more susceptible to Orthopoxviruses because smallpox vaccination has not been available since 1980, which could lead to cross-protection against Mpox virus [16]. Because cases of Mpox have spread to non-endemic countries, transmission in children is likely to occur in community settings, ie at home, in kindergarten or at school, while transmission in adolescents is likely to occur through sexual contact [12,17,18]. In the current outbreak, more cases have been reported in children and adolescents in the region of the Americas than in Africa and Europe, where difficulties in clinical and laboratory diagnosis and access to treatment may be exacerbated by the stigma of disease transmission.…”

Section: Mpox In Children and Adolescentsmentioning

confidence: 99%

Monkeypox virus infections in low-risk groups during the 2022-23 global outbreak: An analysis of the WHO global report

2024

Infez Med

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In the 2022-23 Mpox outbreak, cases also occurred in children, adolescents, and adults aged 50 years and older, for whom the risk of transmission is low and whose epidemiological characteristics are less known, compared to high-risk groups such as young adults. Here we describe the epidemiological characteristics of Mpox in children, adolescents and adults aged 50 years and older in the global Mpox outbreak. Methods. A retrospective study on laboratory-confirmed surveillance data of Mpox cases reported to World Health Organization (WHO) was conducted. Case data from WHO's 2022-23 Mpox Outbreak: Global Trends from 1 January 2022 to 1 September 2023 was used for our analysis. We included cases reported by WHO with data on age (children [range, 0 to 9 years], adolescents [range, 10 to 17 years], adults 50 to 59 years, and adults 60 years and older), gender, WHO region, hospital admission, and intensive care unit admission. Results. Until September 01, 2023, data from 89,752 cases of Mpox have been reported to WHO. Of all the reported cases, 1124 (1.3%), 6296 (7.0%) and 1501 (1.6%) were children and adolescents, adults aged 50-59 years, and adults aged 60 years or older, respectively, and the pro-portion varied among WHO regions. There was a high proportion of cases among population aged 0-17 years, adolescents (256 [66.3%]) from the region of the Americas and girls aged 0-9 years [127 (46.7%)] from the African region. Men aged 50-59 years (3495 [57.2%] vs. 2553 [41.8%] cases from the region of the Americas and the European region, respectively) and men aged 60-69 years (639 [60.0%] vs. 607 [48.4%] from the region of the Americas and the European region) were most affected, compared to other age groups and women. Among children, adolescents, and adults aged 50 years or older, a low proportion of cases developed some complications and required hospital admission, and some cases were admitted to the intensive care unit. Conclusions. Epidemiological evidence of Mpox in these low-risk groups highlights the risk of wider community transmission. Therefore, while efforts continue to control the global outbreak of Mpox in high-risk groups, it is also necessary to ensure that these low-risk groups have access to timely health care and vaccination.

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Section: Mpox In Children and Adolescentsmentioning

confidence: 99%

Monkeypox virus infections in low-risk groups during the 2022-23 global outbreak: An analysis of the WHO global report

2024

Infez Med

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“…The most effective methods for preventing the spread of monkeypox virus include early identification, increasing awareness regarding risk factors, and educating individuals on measures that can lead to reducing contact with the virus [ 8 ]. Young children are at high risk for severe monkeypox disease [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Are pediatric nurses prepared to respond to monkeypox outbreak?

Sadek,

Hendy,

Alhowaymel

et al. 2024

PLoS ONE

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Background Emphasizing the crucial significance of maintaining a national nursing workforce well-prepared with the necessary knowledge, skills, and abilities to respond effectively is the growing frequency of natural and environmental disasters, coupled with public health emergencies such as the COVID-19 pandemic. So, the study aimed to explore pediatric nurses’ preparedness to monkeypox outbreak, and their stress during this outbreak in Egypt. Methods A cross-sectional study was conducted on a 416 nurses direct care for children at selected governmental hospitals in Egypt. Demographic form, Questionnaire for Infectious Disease Outbreak Readiness & Preparedness, factors affecting nurses’ preparedness, and the generalized anxiety disorders scale-7 were the tools of the study. Results (81.5%) of studied nurses had unsatisfactory level of preparedness to monkeypox outbreak. (96.4%) and (95.4%) of them were affected their preparedness by high workload and inconsistent income with the of risk of infection factors. Also, (57.2%) of them had high stress level. Conclusions The study revealed the importance of ensuring adequate supplies of PPE are available and provided, and protocols must be implemented to ensure availability in case of an outbreak. Moreover, nurse staffing levels and workload distribution should be regularly reviewed to create reasonable nurse-patient ratios.

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“…5 Globally, reports of mpox disease in children and adolescents are also reassuring. 6 As of 20 December 2022, across the six World Health Organization regions, only 1.3% (631/49,664) of cases with available detailed data were reported in 0-17 year-olds, 2 including 83 in the United States, 7 and 77 in the European Union and European Economic Area countries. 8 Of these, none had reported exposure in a school setting, 2 highlighting a very low risk of mpox infection in children, especially when compared to adults.…”

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confidence: 99%

Transmission of mpox in educational settings and risk of severe disease in children and adolescents—Let's not make the same mistakes as COVID‐19 again

Karampatsas

Khalil

Heath

et al. 2023

Reviews in Medical Virology

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Monkeypox in children: Update on the current outbreak and need for better reporting

Cited by 7 publications

References 2 publications

Monkeypox virus infections in low-risk groups during the 2022-23 global outbreak: An analysis of the WHO global report

Monkeypox virus infections in low-risk groups during the 2022-23 global outbreak: An analysis of the WHO global report

Are pediatric nurses prepared to respond to monkeypox outbreak?

Transmission of mpox in educational settings and risk of severe disease in children and adolescents—Let's not make the same mistakes as COVID‐19 again

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