Monkeypox

Phasing out monkeypox: mpox is the new name for an old disease

“…Since May 2022, the world has faced the unprecedented spread of monkeypox through continuous chains of human-to-human transmission, with nearly 90,000 cases in over 100 countries. 1 Along with a number of uncertainties and scientific issues, the outbreak has also brought to light unfortunate habits of our society: stigma, racism, and discrimination. 2 , 3 , 4 …”

Global Infectious Diseases in November 2022: Monthly Analysis

“…Omicron subvariants, such as BA.5.2, have gradually spread worldwide [4]. The World Health Organization declared monkeypox an International Public Health Emergency in July 2022, because monkeypox was observed to spread worldwide beyond Africa [5]. Many other infectious diseases, such as dengue, measles, and cholera, are also of concern.…”

Repurposing of the antibiotic nitroxoline for the treatment of mpox

“…Two clades of mpox (previously known as monkeypox) virus, a member of the genus Orthopoxvirus in the family Poxviridae , caused until recently only limited zoonotic outbreaks in Africa [Elsayed et al, 2022; Gessain et al, 2022; Huang et al, 2022; Mitjà et al, 2022; Rabaan et al, 2022]. Currently, mpox viruses considered as clade IIB (occasionally also as clade III, consensus on the nomenclature is still developing) are spreading for the first time by sustained human-to-human transmission outside of Africa [Elsayed et al, 2022; Gessain et al, 2022; Huang et al, 2022; Mitjà et al, 2022; Rabaan et al, 2022].…”

“…Two clades of mpox (previously known as monkeypox) virus, a member of the genus Orthopoxvirus in the family Poxviridae , caused until recently only limited zoonotic outbreaks in Africa [Elsayed et al, 2022; Gessain et al, 2022; Huang et al, 2022; Mitjà et al, 2022; Rabaan et al, 2022]. Currently, mpox viruses considered as clade IIB (occasionally also as clade III, consensus on the nomenclature is still developing) are spreading for the first time by sustained human-to-human transmission outside of Africa [Elsayed et al, 2022; Gessain et al, 2022; Huang et al, 2022; Mitjà et al, 2022; Rabaan et al, 2022]. This ongoing outbreak was classified as a ‘Public Health Emergency of International Concern’ by the WHO on 23 rd July 2022 [Elsayed et al, 2022; Gessain et al, 2022; Huang et al, 2022; Mitjà et al, 2022; Rabaan et al, 2022] and has at the time of writing (29th December 2022) affected at least 110 countries, accounting for 83,539 documented cases and at least 72 deaths [CDC, 2022].…”