“…These include effects on mitochondrial electron transport and oxidative phosphorylation, and inhibition of a number of enzymes involved in energy metabolism (Adeyemo et al, 1982;Tso & Lee, 1982a;Stephens et al, 1983;Kim & Waller, 1984). Much attention has been paid to possible inhibition of the lactate dehydrogenase isoenzyme LDH-C4 Tso & Lee, 1982b;Morris et al, 1986;Whaley et al, 1986). LDH-C4 is composed of male germ cell-specific C subunits (Zinkham, 1968), and inhibition of this isoenzyme would specifically interfere with the metabolism of spermatogenic cells and spermatozoa.…”