Monitoring pregnancy outcomes after prenatal drug exposure through prospective pregnancy registries: A pharmaceutical company commitment

Reiff-Eldridge, Robbin; Heffner, Cindy R.; Ephross, Sara A.; Tennis, Patricia; White, Ayla O.; Andrews, Elizabeth

doi:10.1016/s0002-9378(00)70506-0

Cited by 122 publications

(63 citation statements)

References 2 publications

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“…Over a 14-year period from 1984 to 1998, the Acyclovir in Pregnancy Registry recorded outcomes of pregnancies in which in utero exposure to acyclovir or valacyclovir occurred (74). No differences were seen with respect to fetal outcomes or birth defects, although the numbers of subjects in the registry were too small to draw definitive conclusions.…”

Section: Antiviral Prophylaxis During Pregnancymentioning

confidence: 99%

Neonatal Herpes Simplex Infection

2004

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Tremendous advances have occurred over the past 30 years in the diagnosis and management of neonatal herpes simplex virus (HSV) disease. Mortality in patients with disseminated disease has decreased from 85 to 29%, and that in patients with central nervous system (CNS) disease has decreased from 50 to 4%. Morbidity has been improved more modestly: the proportion of patients with disseminated disease who are developing normally at 1 year has increased from 50 to 83%. While the proportion of patients with neurologic morbidity following CNS disease has remained essentially unchanged over the past three decades, the total number of patients who are developing normally following HSV CNS disease has increased due to the improved survival. Although additional therapeutic advances in the future are possible, more immediate methods for further improvements in outcome for patients with this potentially devastating disease lie in an enhanced awareness of neonatal HSV infection and disease. A thorough understanding of the biology and natural history of HSV in the gravid woman and the neonate provides the basis for such an index of suspicion and is provided in this article

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Section: Antiviral Prophylaxis During Pregnancymentioning

confidence: 99%

Neonatal Herpes Simplex Infection

2004

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“…This compound was excreted in the milk of lactating rats, with a milk/maternal plasma ratio of 0.8:1.1, suggesting that it would be excreted in human milk to a higher degree than other anticonvulsants (Bar-Oz et al, 2000). Use of lamotrigine during pregnancy indicates an incidence of congenital malformations of 6.5% compared with 3 to 5% in controls (Reiff-Eldridge et al, 2000). Clearly, studies are needed to assess the teratogenic potential of these newer compounds when used in monotherapy (Lowe, 2001).…”

mentioning

confidence: 99%

Structural Effects and Neurofunctional Sequelae of Developmental Exposure to Psychotherapeutic Drugs: Experimental and Clinical Aspects

2004

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“…should be tried first to treat migraine in pregnant women because many of the drugs normally used are teratogenic and abortifacient, particularly in the first trimester. Moreover, weight management and lifestyle modifications are advised to reduce feto-maternal complications (24,25). Our study is limited in terms of its sample size.…”

Section: Discussionmentioning

confidence: 97%

Association Between Migraine and Diabetes in Pregnancy

Zain¹,

Mustafa²,

Khan³

et al. 2016

Avicenna J Med Biochem

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Background: Migraine ranks as the eighth most disabling condition and one of the most common causes of headache in Pakistan. Objectives: In this study, we aimed to determine the association between migraine and diabetes in pregnant women. Patients and Methods:This cross-sectional study recruited 498 pregnant women, grouped into pregnant without diabetes (n = 300) and pregnant with diabetes (n = 198) according to the International Association of the Diabetes and Pregnancy Study criteria. Seventy-five women with known migraine were also recruited as positive controls. After confirming that the study subjects had headache at least once a month, the researcher filled out a comprehensive form based on the International Classification of Headache Disorders version II. Migraine disability score was used to assess severity. Fasting blood glucose levels were measured by

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Monitoring pregnancy outcomes after prenatal drug exposure through prospective pregnancy registries: A pharmaceutical company commitment

Cited by 122 publications

References 2 publications

Neonatal Herpes Simplex Infection

Neonatal Herpes Simplex Infection

Structural Effects and Neurofunctional Sequelae of Developmental Exposure to Psychotherapeutic Drugs: Experimental and Clinical Aspects

Association Between Migraine and Diabetes in Pregnancy

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